Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract

Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract

The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and neg...

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Main Author: Alagasamy, Sangeeta Vani
Format: Thesis
Language:English
Published: 2018
Subjects:
RS200-201 Pharmaceutical dosage forms
Online Access:http://eprints.usm.my/44340/1/SANGEETA%20VANI%20ALAGASAMY.pdf
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spelling my-usm-ep.443402019-05-15T02:18:15Z Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract 2018-05 Alagasamy, Sangeeta Vani RS200-201 Pharmaceutical dosage forms The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and negatives bacteria. Firstly, M. ferrea leaf extraction technique was optimized using antimicrobial assay guided method. Powdered freeze dried leaves of M. ferrea (particle size 0.5mm) (1:15w/v) using ultrasonic-assisted technique yielded methanol crude extract with a good antibacterial activity against Staphylococcus aureus, MRSA, Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli. 2018-05 Thesis http://eprints.usm.my/44340/ http://eprints.usm.my/44340/1/SANGEETA%20VANI%20ALAGASAMY.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Penyelidikan Dadah dan Ubat-ubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS200-201 Pharmaceutical dosage forms
spellingShingle RS200-201 Pharmaceutical dosage forms
Alagasamy, Sangeeta Vani
Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
description The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and negatives bacteria. Firstly, M. ferrea leaf extraction technique was optimized using antimicrobial assay guided method. Powdered freeze dried leaves of M. ferrea (particle size 0.5mm) (1:15w/v) using ultrasonic-assisted technique yielded methanol crude extract with a good antibacterial activity against Staphylococcus aureus, MRSA, Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli.
format Thesis
qualification_level Master's degree
author Alagasamy, Sangeeta Vani
author_facet Alagasamy, Sangeeta Vani
author_sort Alagasamy, Sangeeta Vani
title Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_short Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_full Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_fullStr Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_full_unstemmed Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_sort isolation and characterisation of chemical constituents with anti-methicilin resistant staphylococcus aureus activity from mesua ferrea leaf extract
granting_institution Universiti Sains Malaysia
granting_department Pusat Penyelidikan Dadah dan Ubat-ubatan
publishDate 2018
url http://eprints.usm.my/44340/1/SANGEETA%20VANI%20ALAGASAMY.pdf
_version_ 1747821362225872896

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