Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM

Purpose: To correlate the GCS and risk factors with ASPECTS among patients with middle cerebral artery territory ischaemic stroke in HUSM. Materials and methods: In an institutional review board-approved study, the authors obtained 148 samples from medical ward of HUSM. Patients with clinically pro...

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Main Author:	Eie, Teo Yin
Format:	Thesis
Language:	English
Published:	2016
Subjects:	RC31-1245 Internal medicine
Online Access:	http://eprints.usm.my/44360/1/Dr.%20Teo%20Yin%20Eie-24%20pages.pdf
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spelling	my-usm-ep.443602020-10-22T03:03:19Z Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM 2016 Eie, Teo Yin RC31-1245 Internal medicine Purpose: To correlate the GCS and risk factors with ASPECTS among patients with middle cerebral artery territory ischaemic stroke in HUSM. Materials and methods: In an institutional review board-approved study, the authors obtained 148 samples from medical ward of HUSM. Patients with clinically proven stroke and underwent non-contrast enhanced CT brain were recruited. Fasting blood sugar and fasting lipid profiled were obtained. CT brains were reviewed to obtain ASPECTS of each individuals. Correlation and Regression were used to assess the association and prediction between GCS and various risk factors with ASPECTS. Results: We were able to obtain 148 patients whom 140 were Malays, 8 were non-Malays, 48 were male and 100 were female. There was good positive correlation between GCS and ASPECTS (r=0.615, p<0.001). On univariate analysis, only GCS was statistically significant (OR 0.076; 95%CI 0.011 to 0.515, r2 = -2.58, p<0.05). One unit increament in GCS has 92.4% lesser odds to have worse ASPECTS when other confounders were not adjusted. However, multivariate analysis showed none of the variables was statistically significant. Conclusions: We suggested that GCS is associated significantly with ASPECTS and can be applied to predict ASPECTS when other confounders were not added. The risk factors including age, gender, fasting blood sugar, total cholesterol level, triglyceride level, LDL level and HDL level have no correlation with severity of stroke. 2016 Thesis http://eprints.usm.my/44360/ http://eprints.usm.my/44360/1/Dr.%20Teo%20Yin%20Eie-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC31-1245 Internal medicine
spellingShingle	RC31-1245 Internal medicine Eie, Teo Yin Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
description	Purpose: To correlate the GCS and risk factors with ASPECTS among patients with middle cerebral artery territory ischaemic stroke in HUSM. Materials and methods: In an institutional review board-approved study, the authors obtained 148 samples from medical ward of HUSM. Patients with clinically proven stroke and underwent non-contrast enhanced CT brain were recruited. Fasting blood sugar and fasting lipid profiled were obtained. CT brains were reviewed to obtain ASPECTS of each individuals. Correlation and Regression were used to assess the association and prediction between GCS and various risk factors with ASPECTS. Results: We were able to obtain 148 patients whom 140 were Malays, 8 were non-Malays, 48 were male and 100 were female. There was good positive correlation between GCS and ASPECTS (r=0.615, p<0.001). On univariate analysis, only GCS was statistically significant (OR 0.076; 95%CI 0.011 to 0.515, r2 = -2.58, p<0.05). One unit increament in GCS has 92.4% lesser odds to have worse ASPECTS when other confounders were not adjusted. However, multivariate analysis showed none of the variables was statistically significant. Conclusions: We suggested that GCS is associated significantly with ASPECTS and can be applied to predict ASPECTS when other confounders were not added. The risk factors including age, gender, fasting blood sugar, total cholesterol level, triglyceride level, LDL level and HDL level have no correlation with severity of stroke.
format	Thesis
qualification_level	Master's degree
author	Eie, Teo Yin
author_facet	Eie, Teo Yin
author_sort	Eie, Teo Yin
title	Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
title_short	Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
title_full	Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
title_fullStr	Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
title_full_unstemmed	Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM
title_sort	correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in husm
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2016
url	http://eprints.usm.my/44360/1/Dr.%20Teo%20Yin%20Eie-24%20pages.pdf
_version_	1747821365016133632

Correlation of risk factors and aspect scores in patients with middle cerebral artery ischaemic stroke in HUSM

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