Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors

This study focused on the effects of the methanol crude extract of Zizyphus mauritiana leaves and the essential oil of the mesocarp of Myristica fragrans on the function of GABA (A) receptors. Both crude and essential oil were tested on the Xenopus laevis oocytes that comprised of GABA (A) receptors...

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Main Author:	Che Has, Ahmad Tarmizi
Format:	Thesis
Language:	English
Published:	2012
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/44777/1/AHMAD%20TARMIZI.pdf
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id	my-usm-ep.44777
record_format	uketd_dc
spelling	my-usm-ep.447772019-07-01T02:17:29Z Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors 2012-05 Che Has, Ahmad Tarmizi R5-920 Medicine (General) This study focused on the effects of the methanol crude extract of Zizyphus mauritiana leaves and the essential oil of the mesocarp of Myristica fragrans on the function of GABA (A) receptors. Both crude and essential oil were tested on the Xenopus laevis oocytes that comprised of GABA (A) receptors α1β2γ2s subtype. An automated fast perfusion system that applied the two microelectrodes voltage clamp measurement technique at EC5-10 of GABA was used. GABA or gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian central nervous system and involves in the balance between excitation and inhibition in the neuronal cells. 2012-05 Thesis http://eprints.usm.my/44777/ http://eprints.usm.my/44777/1/AHMAD%20TARMIZI.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Che Has, Ahmad Tarmizi Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
description	This study focused on the effects of the methanol crude extract of Zizyphus mauritiana leaves and the essential oil of the mesocarp of Myristica fragrans on the function of GABA (A) receptors. Both crude and essential oil were tested on the Xenopus laevis oocytes that comprised of GABA (A) receptors α1β2γ2s subtype. An automated fast perfusion system that applied the two microelectrodes voltage clamp measurement technique at EC5-10 of GABA was used. GABA or gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian central nervous system and involves in the balance between excitation and inhibition in the neuronal cells.
format	Thesis
qualification_level	Master's degree
author	Che Has, Ahmad Tarmizi
author_facet	Che Has, Ahmad Tarmizi
author_sort	Che Has, Ahmad Tarmizi
title	Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
title_short	Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
title_full	Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
title_fullStr	Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
title_full_unstemmed	Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
title_sort	voltage clamp electrophysiology screening of selected compounds from zizyphus mauritiana and myristica fragrans on specific gaba receptors
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2012
url	http://eprints.usm.my/44777/1/AHMAD%20TARMIZI.pdf
_version_	1747821396353875968

Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors

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