Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect

Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia s...

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Main Author: Torey, Angeline Torey Ayah
Format: Thesis
Language:English
Published: 2012
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Online Access:http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf
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spelling my-usm-ep.447782019-07-01T02:23:57Z Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect 2012-07 Torey, Angeline Torey Ayah R735-854 Medical education. Medical schools. Research Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia spectabilis leaves was evaluated against biofilm-forming C. albicans with the mechanisms of action. The leaf extract was first standardized in terms of authenticity, assay and chemical constituent analysis. Then the antifungal activity of the extract against C. albicans was established by using the disk diffusion and minimum inhibitory concentration (MIC) assay using the broth macrodilution method. 2012-07 Thesis http://eprints.usm.my/44778/ http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf application/pdf en public masters Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Torey, Angeline Torey Ayah
Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
description Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia spectabilis leaves was evaluated against biofilm-forming C. albicans with the mechanisms of action. The leaf extract was first standardized in terms of authenticity, assay and chemical constituent analysis. Then the antifungal activity of the extract against C. albicans was established by using the disk diffusion and minimum inhibitory concentration (MIC) assay using the broth macrodilution method.
format Thesis
qualification_level Master's degree
author Torey, Angeline Torey Ayah
author_facet Torey, Angeline Torey Ayah
author_sort Torey, Angeline Torey Ayah
title Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_short Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_full Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_fullStr Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_full_unstemmed Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_sort possible mechanisms of action and inhibition of biofilm by cassia spectabilis (dc.) methanol leaf extract on candida albicans cells and the cytotoxicity effect
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2012
url http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf
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