Screening For Small Molecule Inhibitors Of p27Kip1 Degradation

Screening For Small Molecule Inhibitors Of p27Kip1 Degradation

In a majority of human cancers, the cyclin-dependent kinase (CDK) inhibitor p27Kip1 is commonly found to be deregulated due to proteolysis by the ubiquitin-proteasome pathway involving the SCFSkp2 E3 ligase. Although proteasome inhibitors act to stabilize p27Kip1, small molecules agents inhibiting t...

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书目详细资料
主要作者:	Ooi, Li Ching
格式:	Thesis
语言:	English
出版:	2012
主题:	QH1 Natural history (General - Including nature conservation geographical distribution)
在线阅读:	http://eprints.usm.my/44880/1/OOI%20LI%20CHING.pdf
标签:	添加标签没有标签, 成为第一个标记此记录!

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