Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts

The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced...

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Main Author: Ali Antisha, Rabyah B.
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf
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spelling my-usm-ep.448842019-07-05T02:26:15Z Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts 2012-06 Ali Antisha, Rabyah B. RS1-441 Pharmacy and materia medica The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats. 2012-06 Thesis http://eprints.usm.my/44884/ http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Ali Antisha, Rabyah B.
Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
description The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats.
format Thesis
qualification_level Master's degree
author Ali Antisha, Rabyah B.
author_facet Ali Antisha, Rabyah B.
author_sort Ali Antisha, Rabyah B.
title Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
title_short Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
title_full Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
title_fullStr Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
title_full_unstemmed Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
title_sort antidiabetic activity of phaleria macrocarpa (scheff.) boerl fruit extracts
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2012
url http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf
_version_ 1747821419229609984