The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures

Keloid is characterized by excess collagen deposition that can damage healthy tissue. With the widespread use of Vitamin E- tocopherols based product and the discovery of tocotrienol (T3) potential to treat various skin injuries; there are possibilities of tocotrienol-rich fraction (TRF) to interced...

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Main Author:	Yusuf, Siti Mahirah
Format:	Thesis
Language:	English
Published:	2012
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/44896/1/SITI%20MAHIRAH%20BINTI%20YUSUF.pdf
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id	my-usm-ep.44896
record_format	uketd_dc
spelling	my-usm-ep.448962019-07-05T08:20:53Z The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures 2012 Yusuf, Siti Mahirah R5-920 Medicine (General) Keloid is characterized by excess collagen deposition that can damage healthy tissue. With the widespread use of Vitamin E- tocopherols based product and the discovery of tocotrienol (T3) potential to treat various skin injuries; there are possibilities of tocotrienol-rich fraction (TRF) to intercede normal, hypertrophic, or keloid scarring during the inflammatory process. However, there is a lack of scientific evidence to validate the efficacy and the therapies of TRF in scar prevention. Thus, this study was carried out to evaluate the beneficial effects of TRF in wound healing and its possible stimulation towards mRNA expression of inducible nitric oxide synthase (iNOS) in keloid human skin keratinocytes and fibroblasts. 2012 Thesis http://eprints.usm.my/44896/ http://eprints.usm.my/44896/1/SITI%20MAHIRAH%20BINTI%20YUSUF.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Yusuf, Siti Mahirah The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
description	Keloid is characterized by excess collagen deposition that can damage healthy tissue. With the widespread use of Vitamin E- tocopherols based product and the discovery of tocotrienol (T3) potential to treat various skin injuries; there are possibilities of tocotrienol-rich fraction (TRF) to intercede normal, hypertrophic, or keloid scarring during the inflammatory process. However, there is a lack of scientific evidence to validate the efficacy and the therapies of TRF in scar prevention. Thus, this study was carried out to evaluate the beneficial effects of TRF in wound healing and its possible stimulation towards mRNA expression of inducible nitric oxide synthase (iNOS) in keloid human skin keratinocytes and fibroblasts.
format	Thesis
qualification_level	Master's degree
author	Yusuf, Siti Mahirah
author_facet	Yusuf, Siti Mahirah
author_sort	Yusuf, Siti Mahirah
title	The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
title_short	The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
title_full	The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
title_fullStr	The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
title_full_unstemmed	The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
title_sort	mrna expression of inducible nitric oxide synthase in keloid using tocotrienol-rich fraction in primary human epidermal keratinocytes and primary human dermal fibroblast cultures
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2012
url	http://eprints.usm.my/44896/1/SITI%20MAHIRAH%20BINTI%20YUSUF.pdf
_version_	1747821421676986368

The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures

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