Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study

Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS...

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Main Author:	Isa, Asmida
Format:	Thesis
Language:	English
Published:	2014
Subjects:	R735-854 Medical education Medical schools Research
Online Access:	http://eprints.usm.my/44991/1/ASMIDA%20ISA.pdf
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id	my-usm-ep.44991
record_format	uketd_dc
spelling	my-usm-ep.449912019-07-22T02:52:28Z Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study 2014-07 Isa, Asmida R735-854 Medical education. Medical schools. Research Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS patients and correlate with its’ haematological findings. A total of 8 patients were recruited. Cytogenetic mresults revealed six normal karyotypes, a karyotype with structural abnormalities (del(5)(q13q33) and a karyotype with complex rearrangement (t(1;11), t(2;11), del(4p), del(5p), del(9p)). By array-CGH technique, known cytogenetic aberrations, complex chromosome aberrations and rare/cryptic aberrations (<5 Mb) were detected. 2014-07 Thesis http://eprints.usm.my/44991/ http://eprints.usm.my/44991/1/ASMIDA%20ISA.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R735-854 Medical education Medical schools Research
spellingShingle	R735-854 Medical education Medical schools Research Isa, Asmida Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
description	Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS patients and correlate with its’ haematological findings. A total of 8 patients were recruited. Cytogenetic mresults revealed six normal karyotypes, a karyotype with structural abnormalities (del(5)(q13q33) and a karyotype with complex rearrangement (t(1;11), t(2;11), del(4p), del(5p), del(9p)). By array-CGH technique, known cytogenetic aberrations, complex chromosome aberrations and rare/cryptic aberrations (<5 Mb) were detected.
format	Thesis
qualification_level	Master's degree
author	Isa, Asmida
author_facet	Isa, Asmida
author_sort	Isa, Asmida
title	Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
title_short	Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
title_full	Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
title_fullStr	Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
title_full_unstemmed	Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
title_sort	molecular cytogenetics of myelodysplastic syndrome – hospital based study
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2014
url	http://eprints.usm.my/44991/1/ASMIDA%20ISA.pdf
_version_	1747821433609781248

Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study

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