Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study
Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS...
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2014
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my-usm-ep.449912019-07-22T02:52:28Z Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study 2014-07 Isa, Asmida R735-854 Medical education. Medical schools. Research Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS patients and correlate with its’ haematological findings. A total of 8 patients were recruited. Cytogenetic mresults revealed six normal karyotypes, a karyotype with structural abnormalities (del(5)(q13q33) and a karyotype with complex rearrangement (t(1;11), t(2;11), del(4p), del(5p), del(9p)). By array-CGH technique, known cytogenetic aberrations, complex chromosome aberrations and rare/cryptic aberrations (<5 Mb) were detected. 2014-07 Thesis http://eprints.usm.my/44991/ http://eprints.usm.my/44991/1/ASMIDA%20ISA.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
R735-854 Medical education Medical schools Research |
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R735-854 Medical education Medical schools Research Isa, Asmida Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| description |
Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS patients and correlate with its’ haematological findings. A total of 8 patients were recruited. Cytogenetic mresults revealed six normal karyotypes, a karyotype with structural abnormalities
(del(5)(q13q33) and a karyotype with complex rearrangement (t(1;11), t(2;11), del(4p), del(5p), del(9p)). By array-CGH technique, known cytogenetic aberrations, complex chromosome aberrations and rare/cryptic aberrations (<5 Mb) were detected. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Isa, Asmida |
| author_facet |
Isa, Asmida |
| author_sort |
Isa, Asmida |
| title |
Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| title_short |
Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| title_full |
Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| title_fullStr |
Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| title_full_unstemmed |
Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study |
| title_sort |
molecular cytogenetics of myelodysplastic syndrome – hospital based study |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Institut Perubatan & Pergigian Termaju |
| publishDate |
2014 |
| url |
http://eprints.usm.my/44991/1/ASMIDA%20ISA.pdf |
| _version_ |
1747821433609781248 |