Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv

The adaptability of Mycobacterium tuberculosis (Mtb) to various environmental changes presented by host immune systems enables its persistence within infected hosts for decades. Various aspects of gene expression regulation in response to environmental stress have been extensively analyzed in Mtb....

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Main Author: Lee, Li Pin
Format: Thesis
Language:English
Published: 2016
Subjects:
Online Access:http://eprints.usm.my/45003/1/LEE%20LI%20PIN.pdf
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spelling my-usm-ep.450032019-07-23T00:52:12Z Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv 2016-09 Lee, Li Pin R735-854 Medical education. Medical schools. Research The adaptability of Mycobacterium tuberculosis (Mtb) to various environmental changes presented by host immune systems enables its persistence within infected hosts for decades. Various aspects of gene expression regulation in response to environmental stress have been extensively analyzed in Mtb. However, the roles of transcriptional start sites (TSSs) and the small regulatory RNAs (sRNAs) in regulating gene expression within Mtb are given very little attention, particularly under stress condition. This ignites the effort to map TSSs and identify sRNAs involved in different stress environments. 2016-09 Thesis http://eprints.usm.my/45003/ http://eprints.usm.my/45003/1/LEE%20LI%20PIN.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Lee, Li Pin
Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
description The adaptability of Mycobacterium tuberculosis (Mtb) to various environmental changes presented by host immune systems enables its persistence within infected hosts for decades. Various aspects of gene expression regulation in response to environmental stress have been extensively analyzed in Mtb. However, the roles of transcriptional start sites (TSSs) and the small regulatory RNAs (sRNAs) in regulating gene expression within Mtb are given very little attention, particularly under stress condition. This ignites the effort to map TSSs and identify sRNAs involved in different stress environments.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Lee, Li Pin
author_facet Lee, Li Pin
author_sort Lee, Li Pin
title Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
title_short Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
title_full Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
title_fullStr Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
title_full_unstemmed Mapping Of Transcriptional Start Site And The Identification Of Novel Srna In Mycobacterium tuberculosis H37Rv
title_sort mapping of transcriptional start site and the identification of novel srna in mycobacterium tuberculosis h37rv
granting_institution Universiti Sains Malaysia
granting_department Institut Perubatan & Pergigian Termaju
publishDate 2016
url http://eprints.usm.my/45003/1/LEE%20LI%20PIN.pdf
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