Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang

Incidence of Diabetes Mellitus (DM) and its associated acute co-morbidities is increasing. However, there is no Diabetic Ketoacidosis (DKA) treatment protocol in Malaysia at this point. There is no baseline data available for DKA in Malaysia as well. This study aims to record incidence rate of...

Full description

Saved in:

Bibliographic Details
Main Author:	Usman, Atif
Format:	Thesis
Language:	English
Published:	2013
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/45057/1/Atif%20Usman24.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.45057
record_format	uketd_dc
spelling	my-usm-ep.450572019-07-24T07:57:28Z Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang 2013-07 Usman, Atif RS1-441 Pharmacy and materia medica Incidence of Diabetes Mellitus (DM) and its associated acute co-morbidities is increasing. However, there is no Diabetic Ketoacidosis (DKA) treatment protocol in Malaysia at this point. There is no baseline data available for DKA in Malaysia as well. This study aims to record incidence rate of DKA and its treatment outcomes in Malaysian population. It is also intended to get an insight of knowledge, attitude and practices of healthcare professionals that are directly involved in management of DM and DKA. For first part, the study was done retrospectively at Hospital Pulau Pinang (HPP). DKA patient profiles were recorded by using universal sampling technique based on inclusion criteria and further analyzed using Statistical Package for Social Sciences (SPSS)® version 16. Of total 132 DKA patients, mean age of patients was 47.7 ± 16.3 years while most admissions were attributed to Malay patients (47%). DKA was more prevalent in T2DM (51.5%) patients followed by hypertension (54.5%) and dyslipidemia (43.0%). Most patients (61.4%) registered complaint of nausea and vomiting, and were accompanied with sepsis (31.9%) whereas attending physicians observed 83.3% patients to be dehydrated. Moreover, with mean blood glucose level at 30.4 ± 13.3 mmol · L-1, arterial pH at 7.15 ± 0.16, arterial bicarbonate at 9.7 ± 5.5 mmol · L-1 and ketones at 4.6 ± 1.7 mmol · L-1, chief DKA biochemical profiles rendered patients to be experiencing moderate episode of DKA, on average. It was also observed that newly diagnosed diabetes mellitus (NDDM) patients, deceased patients and ICU referred patients had more severe event of DKA than the rest of patients. 2013-07 Thesis http://eprints.usm.my/45057/ http://eprints.usm.my/45057/1/Atif%20Usman24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Usman, Atif Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
description	Incidence of Diabetes Mellitus (DM) and its associated acute co-morbidities is increasing. However, there is no Diabetic Ketoacidosis (DKA) treatment protocol in Malaysia at this point. There is no baseline data available for DKA in Malaysia as well. This study aims to record incidence rate of DKA and its treatment outcomes in Malaysian population. It is also intended to get an insight of knowledge, attitude and practices of healthcare professionals that are directly involved in management of DM and DKA. For first part, the study was done retrospectively at Hospital Pulau Pinang (HPP). DKA patient profiles were recorded by using universal sampling technique based on inclusion criteria and further analyzed using Statistical Package for Social Sciences (SPSS)® version 16. Of total 132 DKA patients, mean age of patients was 47.7 ± 16.3 years while most admissions were attributed to Malay patients (47%). DKA was more prevalent in T2DM (51.5%) patients followed by hypertension (54.5%) and dyslipidemia (43.0%). Most patients (61.4%) registered complaint of nausea and vomiting, and were accompanied with sepsis (31.9%) whereas attending physicians observed 83.3% patients to be dehydrated. Moreover, with mean blood glucose level at 30.4 ± 13.3 mmol · L-1, arterial pH at 7.15 ± 0.16, arterial bicarbonate at 9.7 ± 5.5 mmol · L-1 and ketones at 4.6 ± 1.7 mmol · L-1, chief DKA biochemical profiles rendered patients to be experiencing moderate episode of DKA, on average. It was also observed that newly diagnosed diabetes mellitus (NDDM) patients, deceased patients and ICU referred patients had more severe event of DKA than the rest of patients.
format	Thesis
qualification_level	Master's degree
author	Usman, Atif
author_facet	Usman, Atif
author_sort	Usman, Atif
title	Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
title_short	Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
title_full	Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
title_fullStr	Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
title_full_unstemmed	Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang
title_sort	diabetic ketoacidosis: evaluation of therapeutic outcomes, and knowledge, attitude and practices of physicians and pharmacists in hospital pulau pinang
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2013
url	http://eprints.usm.my/45057/1/Atif%20Usman24.pdf
_version_	1747821447284260864

Diabetic Ketoacidosis: Evaluation Of Therapeutic Outcomes, And Knowledge, Attitude And Practices Of Physicians And Pharmacists In Hospital Pulau Pinang

Similar Items