High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A

Increasing numbers of multi-resistance Salmonella typhi cases poses a huge threat especially to ongoing typhoid treatments. This turn of event calls for new treatments against Salmonella typhi. The objectives of this study is to identify potential drug targeted protein from Salmonella typhi using h...

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Main Author:	Tan, Chen Shen
Format:	Thesis
Language:	English
Published:	2015
Subjects:	R735-854 Medical education Medical schools Research
Online Access:	http://eprints.usm.my/45073/1/TAN%20CHEN%20SHEN.pdf
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id	my-usm-ep.45073
record_format	uketd_dc
spelling	my-usm-ep.450732019-07-26T01:17:47Z High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A 2015-10 Tan, Chen Shen R735-854 Medical education. Medical schools. Research Increasing numbers of multi-resistance Salmonella typhi cases poses a huge threat especially to ongoing typhoid treatments. This turn of event calls for new treatments against Salmonella typhi. The objectives of this study is to identify potential drug targeted protein from Salmonella typhi using high throughput virtual screening, and to understand the inhibition mechanism between ligand and protein. This research looks into the high throughput virtual screening of D-alanine-D-alanine ligase A against the ZINC database for potential inhibitors. D-alanine-D-alanine ligase A is a vital enzyme in the peptidoglycan biosynthesis pathway, and being a non-human homolog, 2015-10 Thesis http://eprints.usm.my/45073/ http://eprints.usm.my/45073/1/TAN%20CHEN%20SHEN.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R735-854 Medical education Medical schools Research
spellingShingle	R735-854 Medical education Medical schools Research Tan, Chen Shen High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
description	Increasing numbers of multi-resistance Salmonella typhi cases poses a huge threat especially to ongoing typhoid treatments. This turn of event calls for new treatments against Salmonella typhi. The objectives of this study is to identify potential drug targeted protein from Salmonella typhi using high throughput virtual screening, and to understand the inhibition mechanism between ligand and protein. This research looks into the high throughput virtual screening of D-alanine-D-alanine ligase A against the ZINC database for potential inhibitors. D-alanine-D-alanine ligase A is a vital enzyme in the peptidoglycan biosynthesis pathway, and being a non-human homolog,
format	Thesis
qualification_level	Master's degree
author	Tan, Chen Shen
author_facet	Tan, Chen Shen
author_sort	Tan, Chen Shen
title	High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
title_short	High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
title_full	High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
title_fullStr	High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
title_full_unstemmed	High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
title_sort	high throughput virtual screening for inhibitors of salmonella typhi’s dalanine- d-alanine ligase a
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2015
url	http://eprints.usm.my/45073/1/TAN%20CHEN%20SHEN.pdf
_version_	1747821450684792832

High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A

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