Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography

Introduction: Febrile seizures were the commonest convulsive event during childhood. Currently there is no role of electroencephalography (EEG) study in simple febrile seizure. The precise role of EEG in evaluation of patients with complex febrile seizures (CFS) has not been established. In view...

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Main Author:	Hashim, Mohd Iftitah
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RC31-1245 Internal medicine
Online Access:	http://eprints.usm.my/45248/1/Dr.%20Mohd%20Iftitah%20Hashim-24%20pages.pdf
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spelling	my-usm-ep.452482020-10-22T03:03:14Z Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography 2017 Hashim, Mohd Iftitah RC31-1245 Internal medicine Introduction: Febrile seizures were the commonest convulsive event during childhood. Currently there is no role of electroencephalography (EEG) study in simple febrile seizure. The precise role of EEG in evaluation of patients with complex febrile seizures (CFS) has not been established. In view of increased risk of future epilepsy in these patients, this study determines and to investigate the socio-demographic and clinical characteristics of CFS and its associations with an abnormal EEG outcome. Methods: All available EEG records at Hospital Universiti Sains Malaysia (HUSM) were retrospectively reviewed to identify those EEGs performed for the indication of febrile seizure (January 2005 to December 2015). From this cohort, those patients fulfilling criteria of CFS were selected. The association between socio-demographic, clinical characteristic and abnormal EEG was analysed. Results: A total of 77 patients were selected into the study. Of these, 14 patients (18.2%) had abnormal EEG. The mean age was 34.36±26.28 months, 46 were boys (59.7%) and 31 were girls (40.3%) and most of them were Malay (96.1%). All patients had normal neurological assessment post seizure. With multivariate analysis, frequency of seizure more than 2 episodes within 24-hour was significantly associated to abnormal EEG as compared to one episode of seizure (AOR 4.01, 95% CI 1.02-15.59, p=0.046).Conclusions: The seizure frequency of more than 2 episodes within 24-hour was an important predictor of abnormal EEG and should be an indication for EEG study among CFS patients. This group of patients warrant for further follow-up and monitoring for recurrence of seizure or epilepsy later. 2017 Thesis http://eprints.usm.my/45248/ http://eprints.usm.my/45248/1/Dr.%20Mohd%20Iftitah%20Hashim-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC31-1245 Internal medicine
spellingShingle	RC31-1245 Internal medicine Hashim, Mohd Iftitah Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
description	Introduction: Febrile seizures were the commonest convulsive event during childhood. Currently there is no role of electroencephalography (EEG) study in simple febrile seizure. The precise role of EEG in evaluation of patients with complex febrile seizures (CFS) has not been established. In view of increased risk of future epilepsy in these patients, this study determines and to investigate the socio-demographic and clinical characteristics of CFS and its associations with an abnormal EEG outcome. Methods: All available EEG records at Hospital Universiti Sains Malaysia (HUSM) were retrospectively reviewed to identify those EEGs performed for the indication of febrile seizure (January 2005 to December 2015). From this cohort, those patients fulfilling criteria of CFS were selected. The association between socio-demographic, clinical characteristic and abnormal EEG was analysed. Results: A total of 77 patients were selected into the study. Of these, 14 patients (18.2%) had abnormal EEG. The mean age was 34.36±26.28 months, 46 were boys (59.7%) and 31 were girls (40.3%) and most of them were Malay (96.1%). All patients had normal neurological assessment post seizure. With multivariate analysis, frequency of seizure more than 2 episodes within 24-hour was significantly associated to abnormal EEG as compared to one episode of seizure (AOR 4.01, 95% CI 1.02-15.59, p=0.046).Conclusions: The seizure frequency of more than 2 episodes within 24-hour was an important predictor of abnormal EEG and should be an indication for EEG study among CFS patients. This group of patients warrant for further follow-up and monitoring for recurrence of seizure or epilepsy later.
format	Thesis
qualification_level	Master's degree
author	Hashim, Mohd Iftitah
author_facet	Hashim, Mohd Iftitah
author_sort	Hashim, Mohd Iftitah
title	Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
title_short	Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
title_full	Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
title_fullStr	Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
title_full_unstemmed	Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
title_sort	socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2017
url	http://eprints.usm.my/45248/1/Dr.%20Mohd%20Iftitah%20Hashim-24%20pages.pdf
_version_	1747821476408459264

Socio-demographic and clinical characteristics of complex febrile seizure and its association with abnormal electroencephalography

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