Utilization Of Evidence-Based Therapy For The Secondary Prevention Of Coronary Artery Disease: Predictors And Impact Of Pharmacist-Initiated Interventions
Over the past decades, secondary prevention has played a more and more important role in coronary artery disease management. Among the medications for long-term secondary prevention, antiplatelets, β-blockers, angiotensin-converting enzyme inhibitors (ACEIs), and statins were proven to be high...
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my-usm-ep.452622019-08-22T08:35:21Z Utilization Of Evidence-Based Therapy For The Secondary Prevention Of Coronary Artery Disease: Predictors And Impact Of Pharmacist-Initiated Interventions 2013-07 Kassab, Yaman Walid RS1-441 Pharmacy and materia medica Over the past decades, secondary prevention has played a more and more important role in coronary artery disease management. Among the medications for long-term secondary prevention, antiplatelets, β-blockers, angiotensin-converting enzyme inhibitors (ACEIs), and statins were proven to be highly effective in reducing morbidity and mortality in coronary patients. Malaysian guidelines emphasize the continuous use of these evidence-based medications (EBMs) for long-term treatment after an acute coronary event. Despite the guideline recommendations, studies have reported an underuse of these EBMs in ACS patients. The main objectives of the current study were to: (1) quantify the prescription of EBMs at discharge following an acute coronary event and ongoing use in ambulatory care, (2) evaluate the impact of pharmacist-initiated interventions on improving the prescribing trend of secondary preventive therapies upon discharge, (3) evaluate patients’ adherence to EBMs at an average of two years after discharge, and (4) investigate the relationship between patients’ non-adherence and various predictors. This study adopted an interventional comparative methodology with three phases: pre-intervention, intervention, and follow-up phases. In the pre-intervention phase, a retrospective audit was conducted and a random sample of medical records pertaining to ACS patients admitted to Hospital Pulau Pinang during the period from January 2008 to January 2010 was chosen as the control group. 2013-07 Thesis http://eprints.usm.my/45262/ http://eprints.usm.my/45262/1/Yaman%20Walid%20Kassab24.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi |
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Universiti Sains Malaysia |
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USM Institutional Repository |
| language |
English |
| topic |
RS1-441 Pharmacy and materia medica |
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RS1-441 Pharmacy and materia medica Kassab, Yaman Walid Utilization Of Evidence-Based Therapy For The Secondary Prevention Of Coronary Artery Disease: Predictors And Impact Of Pharmacist-Initiated Interventions |
| description |
Over the past decades, secondary prevention has played a more and more important
role in coronary artery disease management. Among the medications for long-term
secondary prevention, antiplatelets, β-blockers, angiotensin-converting enzyme
inhibitors (ACEIs), and statins were proven to be highly effective in reducing
morbidity and mortality in coronary patients. Malaysian guidelines emphasize the
continuous use of these evidence-based medications (EBMs) for long-term treatment
after an acute coronary event. Despite the guideline recommendations, studies have
reported an underuse of these EBMs in ACS patients. The main objectives of the
current study were to: (1) quantify the prescription of EBMs at discharge following an
acute coronary event and ongoing use in ambulatory care, (2) evaluate the impact of
pharmacist-initiated interventions on improving the prescribing trend of secondary
preventive therapies upon discharge, (3) evaluate patients’ adherence to EBMs at an
average of two years after discharge, and (4) investigate the relationship between
patients’ non-adherence and various predictors. This study adopted an interventional
comparative methodology with three phases: pre-intervention, intervention, and
follow-up phases. In the pre-intervention phase, a retrospective audit was conducted
and a random sample of medical records pertaining to ACS patients admitted to
Hospital Pulau Pinang during the period from January 2008 to January 2010 was
chosen as the control group. |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Kassab, Yaman Walid |
| author_facet |
Kassab, Yaman Walid |
| author_sort |
Kassab, Yaman Walid |
| title |
Utilization Of Evidence-Based Therapy For The Secondary
Prevention Of Coronary Artery Disease: Predictors And
Impact Of Pharmacist-Initiated Interventions |
| title_short |
Utilization Of Evidence-Based Therapy For The Secondary
Prevention Of Coronary Artery Disease: Predictors And
Impact Of Pharmacist-Initiated Interventions |
| title_full |
Utilization Of Evidence-Based Therapy For The Secondary
Prevention Of Coronary Artery Disease: Predictors And
Impact Of Pharmacist-Initiated Interventions |
| title_fullStr |
Utilization Of Evidence-Based Therapy For The Secondary
Prevention Of Coronary Artery Disease: Predictors And
Impact Of Pharmacist-Initiated Interventions |
| title_full_unstemmed |
Utilization Of Evidence-Based Therapy For The Secondary
Prevention Of Coronary Artery Disease: Predictors And
Impact Of Pharmacist-Initiated Interventions |
| title_sort |
utilization of evidence-based therapy for the secondary
prevention of coronary artery disease: predictors and
impact of pharmacist-initiated interventions |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Pengajian Sains Farmasi |
| publishDate |
2013 |
| url |
http://eprints.usm.my/45262/1/Yaman%20Walid%20Kassab24.pdf |
| _version_ |
1747821479592984576 |