Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers

Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers

The immunoproteomic analysis of whole cell protein (WCP) of Mycobacterium tuberculosis complex (MTBC) and non–tuberculous mycobacteria (NTM) was carried out to identify the potential species specific and cross genus conserved species biomarkers present in the mycobacterial species. The WCP of Mycoba...

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Main Author: Razman, Aimi Zafira
Format: Thesis
Language:English
Published: 2017
Subjects:
R735-854 Medical education
Medical schools
Research
Online Access:http://eprints.usm.my/45328/1/AIMI%20ZAFIRA%20RAZMAN.pdf
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spelling my-usm-ep.453282019-09-06T02:04:18Z Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers 2017-01 Razman, Aimi Zafira R735-854 Medical education. Medical schools. Research The immunoproteomic analysis of whole cell protein (WCP) of Mycobacterium tuberculosis complex (MTBC) and non–tuberculous mycobacteria (NTM) was carried out to identify the potential species specific and cross genus conserved species biomarkers present in the mycobacterial species. The WCP of Mycobacterium species were separated using SDS-PAGE and followed by Western blot assay to detect IgM, IgG and IgA immune response in pooled sera of TB patients and healthy subjects as well as the individual sera. The immunoreactive bands in WB assay were divided into 4 region of antigens; (1) above 67 kDa; (2) 67 kDa – 32 kDa; (3) 30 kDa, 28kDa and 26 kDa; and (4) below 25 kDa. 2017-01 Thesis http://eprints.usm.my/45328/ http://eprints.usm.my/45328/1/AIMI%20ZAFIRA%20RAZMAN.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Razman, Aimi Zafira
Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
description The immunoproteomic analysis of whole cell protein (WCP) of Mycobacterium tuberculosis complex (MTBC) and non–tuberculous mycobacteria (NTM) was carried out to identify the potential species specific and cross genus conserved species biomarkers present in the mycobacterial species. The WCP of Mycobacterium species were separated using SDS-PAGE and followed by Western blot assay to detect IgM, IgG and IgA immune response in pooled sera of TB patients and healthy subjects as well as the individual sera. The immunoreactive bands in WB assay were divided into 4 region of antigens; (1) above 67 kDa; (2) 67 kDa – 32 kDa; (3) 30 kDa, 28kDa and 26 kDa; and (4) below 25 kDa.
format Thesis
qualification_level Master's degree
author Razman, Aimi Zafira
author_facet Razman, Aimi Zafira
author_sort Razman, Aimi Zafira
title Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
title_short Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
title_full Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
title_fullStr Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
title_full_unstemmed Immunoproteomic Analysis Of Mycobacterium Tuberculosis And Nontuberculous Mycobacteria Towards The Discovery Of Potential Universal Or Species Specific Biomarkers
title_sort immunoproteomic analysis of mycobacterium tuberculosis and nontuberculous mycobacteria towards the discovery of potential universal or species specific biomarkers
granting_institution Universiti Sains Malaysia
granting_department Institut Perubatan & Pergigian Termaju
publishDate 2017
url http://eprints.usm.my/45328/1/AIMI%20ZAFIRA%20RAZMAN.pdf
_version_ 1747821488165093376

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