Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis

Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high speci...

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Main Author:	Bukari, Bakhtiar Affendi
Format:	Thesis
Language:	English
Published:	2017
Subjects:	R735-854 Medical education Medical schools Research
Online Access:	http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf
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id	my-usm-ep.45354
record_format	uketd_dc
spelling	my-usm-ep.453542019-09-10T02:42:04Z Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis 2017-07 Bukari, Bakhtiar Affendi R735-854 Medical education. Medical schools. Research Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis. 2017-07 Thesis http://eprints.usm.my/45354/ http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R735-854 Medical education Medical schools Research
spellingShingle	R735-854 Medical education Medical schools Research Bukari, Bakhtiar Affendi Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
description	Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis.
format	Thesis
qualification_level	Master's degree
author	Bukari, Bakhtiar Affendi
author_facet	Bukari, Bakhtiar Affendi
author_sort	Bukari, Bakhtiar Affendi
title	Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_short	Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_full	Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_fullStr	Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_full_unstemmed	Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
title_sort	generation and characterisation of rna aptamers against esat6 protein from mycobacterium tuberculosis
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2017
url	http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf
_version_	1747821492550238208

Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis

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