Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model

Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model

Peroxisome proliferator –activated receptor (PPAR)-γ activators are commonly used in type 2 diabetes therapy or even drug research as they improved the sensitivity of insulin receptors in cell. Since ancient, medicinal plants have been used to treat diabetes mellitus and recent research proved the e...

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Main Author: Chuah, Ban Chung
Format: Thesis
Language:English
Published: 2017
Subjects:
RS200-201 Pharmaceutical dosage forms
Online Access:http://eprints.usm.my/45372/1/CHUAH%20BAN%20CHUNG.pdf
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spelling my-usm-ep.453722019-09-11T00:55:38Z Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model 2017 Chuah, Ban Chung RS200-201 Pharmaceutical dosage forms Peroxisome proliferator –activated receptor (PPAR)-γ activators are commonly used in type 2 diabetes therapy or even drug research as they improved the sensitivity of insulin receptors in cell. Since ancient, medicinal plants have been used to treat diabetes mellitus and recent research proved the efficacy of these preparations and some of which are remarkably effective . In this study, anti-type 2 diabetes properties of the methanol extract of a total of 300 Malaysian natural products were subjected to PPARγ transactivation activity assay using liver hepatocellular carcinoma (HepG2) cell as model and the activity was assessed through the intensity of the luminescence produced by peroxisome proliferator response element (PPRE) . 2017 Thesis http://eprints.usm.my/45372/ http://eprints.usm.my/45372/1/CHUAH%20BAN%20CHUNG.pdf application/pdf en public masters Universiti Sains Malaysia Institut Farmaseutikal & Nutraseutikal Malaysia
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS200-201 Pharmaceutical dosage forms
spellingShingle RS200-201 Pharmaceutical dosage forms
Chuah, Ban Chung
Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
description Peroxisome proliferator –activated receptor (PPAR)-γ activators are commonly used in type 2 diabetes therapy or even drug research as they improved the sensitivity of insulin receptors in cell. Since ancient, medicinal plants have been used to treat diabetes mellitus and recent research proved the efficacy of these preparations and some of which are remarkably effective . In this study, anti-type 2 diabetes properties of the methanol extract of a total of 300 Malaysian natural products were subjected to PPARγ transactivation activity assay using liver hepatocellular carcinoma (HepG2) cell as model and the activity was assessed through the intensity of the luminescence produced by peroxisome proliferator response element (PPRE) .
format Thesis
qualification_level Master's degree
author Chuah, Ban Chung
author_facet Chuah, Ban Chung
author_sort Chuah, Ban Chung
title Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
title_short Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
title_full Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
title_fullStr Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
title_full_unstemmed Application Of Cell-Based Screening For The Discovery Of Potential Anti Type 2 Diabetis Candidate From Malaysian Natural Product Using Ppar(Y) Ligand As Model
title_sort application of cell-based screening for the discovery of potential anti type 2 diabetis candidate from malaysian natural product using ppar(y) ligand as model
granting_institution Universiti Sains Malaysia
granting_department Institut Farmaseutikal & Nutraseutikal Malaysia
publishDate 2017
url http://eprints.usm.my/45372/1/CHUAH%20BAN%20CHUNG.pdf
_version_ 1747821496470863872

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