Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor

Antibody immobilisation is the cornerstone of antibody-based assay in biosensing technology which is predominantly used to detect and measure a wide variety of biological analytes, ranging from antigens, biomarkers, allergens and drug substances. As such, specific interactions between antibody and l...

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Main Author: Ng,, Woei Kean
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://eprints.usm.my/45441/1/NG%20WOEI%20KEAN.pdf
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spelling my-usm-ep.454412019-09-17T06:44:13Z Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor 2017-08 Ng,, Woei Kean R735-854 Medical education. Medical schools. Research Antibody immobilisation is the cornerstone of antibody-based assay in biosensing technology which is predominantly used to detect and measure a wide variety of biological analytes, ranging from antigens, biomarkers, allergens and drug substances. As such, specific interactions between antibody and ligands are therefore needed to guarantee highest reproducibility and sensitivity possible. The complexity of pinning antibodies forms the key factor in interfering the outcome of an assay as the recognition molecule, i.e. the antibody itself, may have undergone structural changes and distortion when it is attached to the solid phase. 2017-08 Thesis http://eprints.usm.my/45441/ http://eprints.usm.my/45441/1/NG%20WOEI%20KEAN.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Ng,, Woei Kean
Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
description Antibody immobilisation is the cornerstone of antibody-based assay in biosensing technology which is predominantly used to detect and measure a wide variety of biological analytes, ranging from antigens, biomarkers, allergens and drug substances. As such, specific interactions between antibody and ligands are therefore needed to guarantee highest reproducibility and sensitivity possible. The complexity of pinning antibodies forms the key factor in interfering the outcome of an assay as the recognition molecule, i.e. the antibody itself, may have undergone structural changes and distortion when it is attached to the solid phase.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Ng,, Woei Kean
author_facet Ng,, Woei Kean
author_sort Ng,, Woei Kean
title Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
title_short Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
title_full Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
title_fullStr Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
title_full_unstemmed Development Of Antibody Immobilisation Strategy Using Recombinant Human Neonatal Fc Receptor
title_sort development of antibody immobilisation strategy using recombinant human neonatal fc receptor
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2017
url http://eprints.usm.my/45441/1/NG%20WOEI%20KEAN.pdf
_version_ 1747821511089061888