Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar

Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compou...

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主要作者: Md Yusoff, Nor Adlin
格式: Thesis
語言:English
出版: 2017
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在線閱讀:http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf
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spelling my-usm-ep.454462019-09-17T07:03:10Z Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar 2017-02 Md Yusoff, Nor Adlin RS1-441 Pharmacy and materia medica Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded. 2017-02 Thesis http://eprints.usm.my/45446/ http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Md Yusoff, Nor Adlin
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
description Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Md Yusoff, Nor Adlin
author_facet Md Yusoff, Nor Adlin
author_sort Md Yusoff, Nor Adlin
title Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_short Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_full Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_fullStr Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_full_unstemmed Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
title_sort antidiabetic activity of nypa fruticans wurmb. vinegar
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2017
url http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf
_version_ 1747821512316944384