Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar
Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compou...
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| Language: | English |
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2017
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my-usm-ep.454462019-09-17T07:03:10Z Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar 2017-02 Md Yusoff, Nor Adlin RS1-441 Pharmacy and materia medica Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded. 2017-02 Thesis http://eprints.usm.my/45446/ http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
RS1-441 Pharmacy and materia medica |
| spellingShingle |
RS1-441 Pharmacy and materia medica Md Yusoff, Nor Adlin Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| description |
Nypa fruticans Wurmb. vinegar, locally known as nipa palm vinegar (NPV) in Malaysia, is believed to have remarkable antidiabetic properties. This study sought to elucidate the vinegar’s antidiabetic activity and possible mechanisms of action. Liquid– liquid extraction was used to separate the compounds in NPV based on polarity into an ethyl acetate extract (EE) and an aqueous extract (AE). AE was further fractionated using acid hydrolysis into two sub-fractions: SFI and SFII. NPV, EE, AE, SFI and SFII were administered using oral gavage in non diabetic and/or diabetic rats induced by streptozotocin (STZ). Blood glucose levels (BGLs), insulin levels, and liver and pancreatic histological changes were recorded. |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Md Yusoff, Nor Adlin |
| author_facet |
Md Yusoff, Nor Adlin |
| author_sort |
Md Yusoff, Nor Adlin |
| title |
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| title_short |
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| title_full |
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| title_fullStr |
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| title_full_unstemmed |
Antidiabetic Activity Of Nypa Fruticans WURMB. Vinegar |
| title_sort |
antidiabetic activity of nypa fruticans wurmb. vinegar |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Pengajian Sains Farmasi |
| publishDate |
2017 |
| url |
http://eprints.usm.my/45446/1/NOR%20ADLIN%20MD%20YUSOFF.pdf |
| _version_ |
1747821512316944384 |