Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020

Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer...

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Main Author:	Hambali, Norhafini
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RS200-201 Pharmaceutical dosage forms
Online Access:	http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf
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id	my-usm-ep.45453
record_format	uketd_dc
spelling	my-usm-ep.454532019-09-18T01:04:07Z Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 2017-03 Hambali, Norhafini RS200-201 Pharmaceutical dosage forms Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer as implantable and absorbable biomaterial. However, biosynthesis of P(3HB-co-4HB) in single-stage cultivation produces low 4HB unit composition with low productivity. Cupriavidus sp. USMAA1020, a bacterium isolated from Malaysian environment, was capable to synthesize P(3HB-co-4HB) with different 4HB unit compositions but only to a maximum of 70 mol% through single-stage cultivation. 2017-03 Thesis http://eprints.usm.my/45453/ http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf application/pdf en public masters Universiti Sains Malaysia Institut Farmaseutikal & Nutraseutikal Malaysia
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS200-201 Pharmaceutical dosage forms
spellingShingle	RS200-201 Pharmaceutical dosage forms Hambali, Norhafini Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
description	Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer as implantable and absorbable biomaterial. However, biosynthesis of P(3HB-co-4HB) in single-stage cultivation produces low 4HB unit composition with low productivity. Cupriavidus sp. USMAA1020, a bacterium isolated from Malaysian environment, was capable to synthesize P(3HB-co-4HB) with different 4HB unit compositions but only to a maximum of 70 mol% through single-stage cultivation.
format	Thesis
qualification_level	Master's degree
author	Hambali, Norhafini
author_facet	Hambali, Norhafini
author_sort	Hambali, Norhafini
title	Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
title_short	Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
title_full	Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
title_fullStr	Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
title_full_unstemmed	Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
title_sort	enhanced production of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) with high 4hb unit composition using transformant cupriavidus sp.usmaa1020
granting_institution	Universiti Sains Malaysia
granting_department	Institut Farmaseutikal & Nutraseutikal Malaysia
publishDate	2017
url	http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf
_version_	1747821513522806784

Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020

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