The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach

Acute ischemic stroke is a global health problem and is among the leading causes of morbidity and mortality. As prevention is considered the mainstay of management for acute ischemic stroke, knowledge should be highlighted regarding the scientific evidence behind the use of preventive medications an...

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Main Author:	Al-Jabi, Samah W. A. Zyoud
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/45678/1/SAMAH%20W.%20A.%20ZYOUD_HJ.pdf
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id	my-usm-ep.45678
record_format	uketd_dc
spelling	my-usm-ep.456782019-10-17T07:19:50Z The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach 2011-12 Al-Jabi, Samah W. A. Zyoud RS1-441 Pharmacy and materia medica Acute ischemic stroke is a global health problem and is among the leading causes of morbidity and mortality. As prevention is considered the mainstay of management for acute ischemic stroke, knowledge should be highlighted regarding the scientific evidence behind the use of preventive medications and their impact on patients’ outcomes. The objective of the study is to evaluate the impact of the previous use of angiotensin-converting enzyme inhibitor (ACEI), antiplatelet and statin, either alone or in combinations on reducing in-hospital mortality rates, improving functional status at discharge and reducing complications after ischemic stroke. In addition, the independent factors associated with the occurrence of these ischemic stroke outcomes have been investigated. An observational retrospective cohort design was used for all acute ischemic stroke patients admitted to Hospital Pulau Pinang during the period from January 1st 2008 to June 30th 2009. Data included socio-demographic characteristics, clinical characteristics, and previous medication classes, with particular attention being paid to antiplatelets, ACEIs and statins. Impact of the previous use of these medications on ischemic stroke outcomes included: the in-hospital mortality rate, a good functional status as defined by the Barthel Index (BI) > 75, and post-stroke complications, was evaluated after controlling for other variables (i.e. socio-demographic, clinical characteristics, risk factors and other medications) that might have confounded the effects of these preventive medications on ischemic stroke outcomes. 2011-12 Thesis http://eprints.usm.my/45678/ http://eprints.usm.my/45678/1/SAMAH%20W.%20A.%20ZYOUD_HJ.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Al-Jabi, Samah W. A. Zyoud The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
description	Acute ischemic stroke is a global health problem and is among the leading causes of morbidity and mortality. As prevention is considered the mainstay of management for acute ischemic stroke, knowledge should be highlighted regarding the scientific evidence behind the use of preventive medications and their impact on patients’ outcomes. The objective of the study is to evaluate the impact of the previous use of angiotensin-converting enzyme inhibitor (ACEI), antiplatelet and statin, either alone or in combinations on reducing in-hospital mortality rates, improving functional status at discharge and reducing complications after ischemic stroke. In addition, the independent factors associated with the occurrence of these ischemic stroke outcomes have been investigated. An observational retrospective cohort design was used for all acute ischemic stroke patients admitted to Hospital Pulau Pinang during the period from January 1st 2008 to June 30th 2009. Data included socio-demographic characteristics, clinical characteristics, and previous medication classes, with particular attention being paid to antiplatelets, ACEIs and statins. Impact of the previous use of these medications on ischemic stroke outcomes included: the in-hospital mortality rate, a good functional status as defined by the Barthel Index (BI) > 75, and post-stroke complications, was evaluated after controlling for other variables (i.e. socio-demographic, clinical characteristics, risk factors and other medications) that might have confounded the effects of these preventive medications on ischemic stroke outcomes.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Al-Jabi, Samah W. A. Zyoud
author_facet	Al-Jabi, Samah W. A. Zyoud
author_sort	Al-Jabi, Samah W. A. Zyoud
title	The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
title_short	The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
title_full	The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
title_fullStr	The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
title_full_unstemmed	The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach
title_sort	impact of preventive medications and factors related to acute ischemic stroke on outcomes : multimodal preventive medication approach
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2011
url	http://eprints.usm.my/45678/1/SAMAH%20W.%20A.%20ZYOUD_HJ.pdf
_version_	1747821545054535680

The Impact Of Preventive Medications And Factors Related To Acute Ischemic Stroke On Outcomes : Multimodal Preventive Medication Approach

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