Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of...
Saved in:
Main Author: | |
---|---|
Format: | Thesis |
Language: | English |
Published: |
2011
|
Subjects: | |
Online Access: | http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my-usm-ep.45680 |
---|---|
record_format |
uketd_dc |
spelling |
my-usm-ep.456802019-10-17T07:41:30Z Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes 2011-07 Aziz, Salmi Ab R735-854 Medical education. Medical schools. Research Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters. 2011-07 Thesis http://eprints.usm.my/45680/ http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan |
institution |
Universiti Sains Malaysia |
collection |
USM Institutional Repository |
language |
English |
topic |
R735-854 Medical education Medical schools Research |
spellingShingle |
R735-854 Medical education Medical schools Research Aziz, Salmi Ab Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
description |
Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Aziz, Salmi Ab |
author_facet |
Aziz, Salmi Ab |
author_sort |
Aziz, Salmi Ab |
title |
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
title_short |
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
title_full |
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
title_fullStr |
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
title_full_unstemmed |
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes |
title_sort |
arterial stiffness, inflammatory and atherogenic markers in gestational diabetes |
granting_institution |
Universiti Sains Malaysia |
granting_department |
Pusat Pengajian Sains Perubatan |
publishDate |
2011 |
url |
http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf |
_version_ |
1747821545549463552 |