Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes

Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of...

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Main Author: Aziz, Salmi Ab
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf
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spelling my-usm-ep.456802019-10-17T07:41:30Z Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes 2011-07 Aziz, Salmi Ab R735-854 Medical education. Medical schools. Research Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters. 2011-07 Thesis http://eprints.usm.my/45680/ http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Aziz, Salmi Ab
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
description Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters.
format Thesis
qualification_level Master's degree
author Aziz, Salmi Ab
author_facet Aziz, Salmi Ab
author_sort Aziz, Salmi Ab
title Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_short Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_full Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_fullStr Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_full_unstemmed Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_sort arterial stiffness, inflammatory and atherogenic markers in gestational diabetes
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2011
url http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf
_version_ 1747821545549463552