Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions

Non-alcoholic fatty liver disease is one of the most common liver disorders worldwide. However, no data from systematic studies are available for Malaysia on prevalence or rate of this disease. In the present study 180 walk-in mildly hypercholesterolemic adults of both genders were screened usin...

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Main Author:	Magosso, Enrico
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/45705/1/Enrico%20Magosso_HJ.pdf
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spelling	my-usm-ep.457052019-10-23T07:31:56Z Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions 2011 Magosso, Enrico RS1-441 Pharmacy and materia medica Non-alcoholic fatty liver disease is one of the most common liver disorders worldwide. However, no data from systematic studies are available for Malaysia on prevalence or rate of this disease. In the present study 180 walk-in mildly hypercholesterolemic adults of both genders were screened using ultrasound imaging to determine the presence of non-alcoholic fatty liver. The rate of this hepatic disease was found to be high, since it was diagnosed in almost 60% of the participants. Non-alcoholic fatty liver disease consists of fat infiltration in the liver, at present no pharmacological treatment is available. The screening was part of the recruitment process for a double-blind placebocontrolled study aimed at evaluating the activity of tocotrienols for the treatment of non-alcoholic fatty liver disease. Tocotrienols, that are extracted from palm oil, are members of the vitamin E family. Evaluation of the effects of tocotrienols for treatment of non-alcoholic fatty liver disease was performed by comparing liver echogenicity at baseline and at conclusion of the study. Liver hyperechogenicity is proportional to the fat content. 2011 Thesis http://eprints.usm.my/45705/ http://eprints.usm.my/45705/1/Enrico%20Magosso_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Magosso, Enrico Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
description	Non-alcoholic fatty liver disease is one of the most common liver disorders worldwide. However, no data from systematic studies are available for Malaysia on prevalence or rate of this disease. In the present study 180 walk-in mildly hypercholesterolemic adults of both genders were screened using ultrasound imaging to determine the presence of non-alcoholic fatty liver. The rate of this hepatic disease was found to be high, since it was diagnosed in almost 60% of the participants. Non-alcoholic fatty liver disease consists of fat infiltration in the liver, at present no pharmacological treatment is available. The screening was part of the recruitment process for a double-blind placebocontrolled study aimed at evaluating the activity of tocotrienols for the treatment of non-alcoholic fatty liver disease. Tocotrienols, that are extracted from palm oil, are members of the vitamin E family. Evaluation of the effects of tocotrienols for treatment of non-alcoholic fatty liver disease was performed by comparing liver echogenicity at baseline and at conclusion of the study. Liver hyperechogenicity is proportional to the fat content.
format	Thesis
qualification_level	Master's degree
author	Magosso, Enrico
author_facet	Magosso, Enrico
author_sort	Magosso, Enrico
title	Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
title_short	Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
title_full	Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
title_fullStr	Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
title_full_unstemmed	Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions
title_sort	evaluation of the hepatoprotective effects of tocotrienols an the relationship between non-alcoholic fatty liver and brain white-matter lesions
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2011
url	http://eprints.usm.my/45705/1/Enrico%20Magosso_HJ.pdf
_version_	1747821549933559808

Evaluation Of The Hepatoprotective Effects Of Tocotrienols An The Relationship Between Non-Alcoholic Fatty Liver And Brain White-Matter Lesions

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