Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants

Plants with medicinal values are known to possess bioactive compounds and contributed greatly to the existence of several currently available pharmaceuticals. In view of this the present study was conducted to evaluate the antioxidant, antinociceptive and antimicrobial activities of traditionally us...

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Main Author:	Venkatappa, Annegowda Hardur
Format:	Thesis
Language:	English
Published:	2014
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/46382/1/Annegowda%20Hardur%20Venkatappa24.pdf
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id	my-usm-ep.46382
record_format	uketd_dc
spelling	my-usm-ep.463822020-02-28T02:42:19Z Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants 2014-02 Venkatappa, Annegowda Hardur R5-920 Medicine (General) Plants with medicinal values are known to possess bioactive compounds and contributed greatly to the existence of several currently available pharmaceuticals. In view of this the present study was conducted to evaluate the antioxidant, antinociceptive and antimicrobial activities of traditionally used local plants like Terminalia catappa, Piper betle, Bauhinia purpurea, Cinnamomum iners and Callicarpa furfuracea. In this study sonication, maceration and soxhlet extraction techniques were used to obtain their respective plant extracts. The in vitro antioxidant, antimicrobial activity and polyphenolic content determination revealed the presence of significant biological activities and phenolic content in the extract obtained by sonication followed by maceration and soxhlet extraction. Among the plant extracts studied for antioxidant activity, T. catappa extract showed remarkable antioxidant activity followed by P. betle, B. purpurea, C. iners and C. furfuracea extracts. The antioxidant activity displayed by T. catappa extract was significantly higher than commercially available grape seed extract and synthetic antioxidant butylated hydroxytoluene. In addition, T. catappa extract also revealed marked antimicrobial activity against both Gram-positive and Gram-negative bacterial strains followed by B. purpurea, P. betle and C. iners. Soxhlet ethanolic extract of C. furfuracea leaf, stem and root possessed least polyphenolic content, antioxidant and antimicrobial activities when compared with other plant extracts. This is the first ever study regarding the biological investigations of C. furfuracea. 2014-02 Thesis http://eprints.usm.my/46382/ http://eprints.usm.my/46382/1/Annegowda%20Hardur%20Venkatappa24.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Penyelidikan Dadah dan Ubat-ubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Venkatappa, Annegowda Hardur Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
description	Plants with medicinal values are known to possess bioactive compounds and contributed greatly to the existence of several currently available pharmaceuticals. In view of this the present study was conducted to evaluate the antioxidant, antinociceptive and antimicrobial activities of traditionally used local plants like Terminalia catappa, Piper betle, Bauhinia purpurea, Cinnamomum iners and Callicarpa furfuracea. In this study sonication, maceration and soxhlet extraction techniques were used to obtain their respective plant extracts. The in vitro antioxidant, antimicrobial activity and polyphenolic content determination revealed the presence of significant biological activities and phenolic content in the extract obtained by sonication followed by maceration and soxhlet extraction. Among the plant extracts studied for antioxidant activity, T. catappa extract showed remarkable antioxidant activity followed by P. betle, B. purpurea, C. iners and C. furfuracea extracts. The antioxidant activity displayed by T. catappa extract was significantly higher than commercially available grape seed extract and synthetic antioxidant butylated hydroxytoluene. In addition, T. catappa extract also revealed marked antimicrobial activity against both Gram-positive and Gram-negative bacterial strains followed by B. purpurea, P. betle and C. iners. Soxhlet ethanolic extract of C. furfuracea leaf, stem and root possessed least polyphenolic content, antioxidant and antimicrobial activities when compared with other plant extracts. This is the first ever study regarding the biological investigations of C. furfuracea.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Venkatappa, Annegowda Hardur
author_facet	Venkatappa, Annegowda Hardur
author_sort	Venkatappa, Annegowda Hardur
title	Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
title_short	Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
title_full	Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
title_fullStr	Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
title_full_unstemmed	Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
title_sort	comparative evaluation of analgesic, antioxidant and antimicrobial activities of five selected medicinal plants
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Penyelidikan Dadah dan Ubat-ubatan
publishDate	2014
url	http://eprints.usm.my/46382/1/Annegowda%20Hardur%20Venkatappa24.pdf
_version_	1747821660252143616

Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants

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