Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients

Advances in radiotherapy technology has made it possible to deliver highly conformal Intensity Modulated Radiotherapy (IMRT) beam to treat patient with improved setup accuracy using Image Guided Radiotherapy (IGRT). This retrospective study investigates the accuracy of IG-IMRT treatment for 25 head...

Full description

Saved in:

Bibliographic Details
Main Author:	M Zamri, Nada' Alia
Format:	Thesis
Language:	English
Published:	2019
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/46407/1/NADA%20%E2%80%98ALIA%20BINTI%20M%20ZAMRI_HJ.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.46407
record_format	uketd_dc
spelling	my-usm-ep.464072020-03-02T02:44:12Z Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients 2019-07 M Zamri, Nada' Alia R Medicine (General) Advances in radiotherapy technology has made it possible to deliver highly conformal Intensity Modulated Radiotherapy (IMRT) beam to treat patient with improved setup accuracy using Image Guided Radiotherapy (IGRT). This retrospective study investigates the accuracy of IG-IMRT treatment for 25 head and neck cancer (HNC) patients in Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia. An ionisation chamber array detector has been characterised and used for patient specific IMRT QA. The characterisation study shows the doses measured using ionisation chamber array detector were within 2% compared with the doses calculated from the treatment planning system (TPS). All 25 IMRT treatment obtained percentage pass rate ≥95% when 3%/3 mm gamma criteria were used. The geometrical accuracy of the treatment was also analysed based on setup errors measured using kV cone beam CT based-IGRT. A total of 231 pre-treatment CBCT imaging were acquired prior to treatment and compared to the reference CT. PTV margin of ≥3 mm in RL direction, SI direction and AP direction is required if no setup correction was performed. Offline setup protocols; NAL and eNAL were simulated on the setup errors recorded. The eNAL protocol recorded the smallest setup error in all three directions; which were 1.59 mm for RL direction, 2.13 mm for SI direction and 1.61 mm for AP direction. The impact of setup errors on dose distributions was also assessed on six HNC patients. 2019-07 Thesis http://eprints.usm.my/46407/ http://eprints.usm.my/46407/1/NADA%20%E2%80%98ALIA%20BINTI%20M%20ZAMRI_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) M Zamri, Nada' Alia Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
description	Advances in radiotherapy technology has made it possible to deliver highly conformal Intensity Modulated Radiotherapy (IMRT) beam to treat patient with improved setup accuracy using Image Guided Radiotherapy (IGRT). This retrospective study investigates the accuracy of IG-IMRT treatment for 25 head and neck cancer (HNC) patients in Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia. An ionisation chamber array detector has been characterised and used for patient specific IMRT QA. The characterisation study shows the doses measured using ionisation chamber array detector were within 2% compared with the doses calculated from the treatment planning system (TPS). All 25 IMRT treatment obtained percentage pass rate ≥95% when 3%/3 mm gamma criteria were used. The geometrical accuracy of the treatment was also analysed based on setup errors measured using kV cone beam CT based-IGRT. A total of 231 pre-treatment CBCT imaging were acquired prior to treatment and compared to the reference CT. PTV margin of ≥3 mm in RL direction, SI direction and AP direction is required if no setup correction was performed. Offline setup protocols; NAL and eNAL were simulated on the setup errors recorded. The eNAL protocol recorded the smallest setup error in all three directions; which were 1.59 mm for RL direction, 2.13 mm for SI direction and 1.61 mm for AP direction. The impact of setup errors on dose distributions was also assessed on six HNC patients.
format	Thesis
qualification_level	Master's degree
author	M Zamri, Nada' Alia
author_facet	M Zamri, Nada' Alia
author_sort	M Zamri, Nada' Alia
title	Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
title_short	Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
title_full	Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
title_fullStr	Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
title_full_unstemmed	Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients
title_sort	dosimetric and geometric accuracy of image guided intensity modulated radiotherapy (ig-imrt) in head and neck cancer patients
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2019
url	http://eprints.usm.my/46407/1/NADA%20%E2%80%98ALIA%20BINTI%20M%20ZAMRI_HJ.pdf
_version_	1747821663664209920

Dosimetric And Geometric Accuracy Of Image Guided Intensity Modulated Radiotherapy (IG-IMRT) In Head And Neck Cancer Patients

Similar Items