$Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population$

Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population

Objective: To determine the value of apparent diffusion coefficient (ADC), and fractional anisotropy (FA) of the rotator cuff muscles using a 3-Tesla MRI in healthy subjects and comparing its differences. Materials and Methods: Thirty-eight healthy volunteers were included in this prospective st...

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Main Author:	Yusof, Mohd Fariq Mohd
Format:	Thesis
Language:	English
Published:	2018
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/46435/1/Dr.%20Mohd%20Fariq%20Mohd%20Yusof-24%20pages.pdf
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spelling	my-usm-ep.464352020-03-04T08:39:23Z Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population 2018 Yusof, Mohd Fariq Mohd R Medicine (General) Objective: To determine the value of apparent diffusion coefficient (ADC), and fractional anisotropy (FA) of the rotator cuff muscles using a 3-Tesla MRI in healthy subjects and comparing its differences. Materials and Methods: Thirty-eight healthy volunteers were included in this prospective study. Diffusion tensor magnetic resonance imaging (DT MRI) of the rotator cuff muscles were performed. Single-shot spin-echo echo-planar imaging sequences in 32 diffusion directions with a b-value of 400 s/mm2, was selected as most optimal for this study. Subsequently ADC and FA values of the rotator cuff muscles were acquired from the sagittal oblique view of the shoulder by manually drawing an elliptical range of interest of the visualised muscles. Statistical analysis carried out using One-Way ANOVA post-hoc Scheffe test. Measurement was taken by two ratters to reduce bias. Results: Mean ADC with standard deviation of the supraspinatus was 1.63 (±0.12), infraspinatus was 1.61 (±0.09) and subscapularis muscle was 1.74 (±0.15). Mean FA with standard deviation of the supraspinatus was 0.45 (±0.05), infraspinatus was 0.41 (±0.36), subscapularis muscle was 0.47 (±0.55). Mean difference of ADC between supraspinatus and subscapularis muscles as well as subscapularis and infraspinatus muscles were significantly different. The mean ADC between the Supraspinatus and infraspinatus muscles mean difference were similar. Mean difference of FA between all 3 pairs of muscles were significantly different. Intraclass Coefficient for FA and ADC between 2 Raters ranges from good to excellent results. Conclusion: This study has been able to obtain normal range of values of FA and ADC. Among healthy subjects using DTI on a 3-Tesla MRI. These two means are reliable. 2018 Thesis http://eprints.usm.my/46435/ http://eprints.usm.my/46435/1/Dr.%20Mohd%20Fariq%20Mohd%20Yusof-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Yusof, Mohd Fariq Mohd Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
description	Objective: To determine the value of apparent diffusion coefficient (ADC), and fractional anisotropy (FA) of the rotator cuff muscles using a 3-Tesla MRI in healthy subjects and comparing its differences. Materials and Methods: Thirty-eight healthy volunteers were included in this prospective study. Diffusion tensor magnetic resonance imaging (DT MRI) of the rotator cuff muscles were performed. Single-shot spin-echo echo-planar imaging sequences in 32 diffusion directions with a b-value of 400 s/mm2, was selected as most optimal for this study. Subsequently ADC and FA values of the rotator cuff muscles were acquired from the sagittal oblique view of the shoulder by manually drawing an elliptical range of interest of the visualised muscles. Statistical analysis carried out using One-Way ANOVA post-hoc Scheffe test. Measurement was taken by two ratters to reduce bias. Results: Mean ADC with standard deviation of the supraspinatus was 1.63 (±0.12), infraspinatus was 1.61 (±0.09) and subscapularis muscle was 1.74 (±0.15). Mean FA with standard deviation of the supraspinatus was 0.45 (±0.05), infraspinatus was 0.41 (±0.36), subscapularis muscle was 0.47 (±0.55). Mean difference of ADC between supraspinatus and subscapularis muscles as well as subscapularis and infraspinatus muscles were significantly different. The mean ADC between the Supraspinatus and infraspinatus muscles mean difference were similar. Mean difference of FA between all 3 pairs of muscles were significantly different. Intraclass Coefficient for FA and ADC between 2 Raters ranges from good to excellent results. Conclusion: This study has been able to obtain normal range of values of FA and ADC. Among healthy subjects using DTI on a 3-Tesla MRI. These two means are reliable.
format	Thesis
qualification_level	Master's degree
author	Yusof, Mohd Fariq Mohd
author_facet	Yusof, Mohd Fariq Mohd
author_sort	Yusof, Mohd Fariq Mohd
title	Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
title_short	Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
title_full	Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
title_fullStr	Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
title_full_unstemmed	Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population
title_sort	apparent coefficient diffusion (adc) and fractional anisotropy (fa) values of the rotator cuff muscles using dti at 3-tesla mri in the healthy population
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2018
url	http://eprints.usm.my/46435/1/Dr.%20Mohd%20Fariq%20Mohd%20Yusof-24%20pages.pdf
_version_	1747821670280724480

Apparent coefficient diffusion (ADC) and fractional anisotropy (FA) values of the rotator cuff muscles using DTI at 3-Tesla MRI in the healthy population

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