Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)

Background: Digital subtraction angiography (DSA) remains the gold standard in diagnosing complicated peripheral vascular disease and is the only imaging modality capable of visualizing endovascular treatments in all contexts. The purpose of the study is determine the means different of arterial...

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Main Author:	Hamzah, Mohd Helmi
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RC666-701 Diseases of the circulatory (Cardiovascular) system
Online Access:	http://eprints.usm.my/46464/1/Dr.%20Mohd%20Helmi%20Hamzah-24%20pages.pdf
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spelling	my-usm-ep.464642020-03-08T06:55:01Z Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow) 2018 Hamzah, Mohd Helmi RC666-701 Diseases of the circulatory (Cardiovascular) system Background: Digital subtraction angiography (DSA) remains the gold standard in diagnosing complicated peripheral vascular disease and is the only imaging modality capable of visualizing endovascular treatments in all contexts. The purpose of the study is determine the means different of arterial flow time (FT) of DSA on the lower limb circulation pre and post successful revascularization using time density curve (TDC) on syngo iFlow application. Methodology: A total of 45 patients, retrospectively review the pre and post successful revascularization blood flow time using syngo iFlow application. The blood flow time (TTP) of the successful arterial flow is determined by using the application. Mean and SDs were obtained for each measurement, and level of significance for pre and post treatment was studied (P < 0.05). Result: In total of 45 subject was studied (26 male, 19 female, means age 59.3). Stenoses were graded as follows based on the angiographic finding: less than 50% stenosis 2 patients; 50-75% stenosis 37patients; 76-99%, 6 patients. There was a significant difference in means between proximal and distal stenosis for pre treatment (p-value<0.001). The mean difference of pre treatment was -0.84 with mean(SD) for pre and post stenotic segment were 3.94s(0.43) and 4.78s(0.80) respectively. There was also significant mean difference between proximal and distal stenosis for post treatment ( p-value<0.001). The mean difference of post treatment was -0.34 with mean(SD) for pre and post stenotic segment were 3.90s(0.39) and 4.16s(0.52) respectively. Before treatment, means TTP time (time to peak time) between contrast time curve proximal and distal to the treated vessels segment was 3.94s and 4.78s respectively, after treatment was 3.90s and 4.156s respectively. Gain percentage of the improvement time was highest at 62% (n=10), second most 83% (n=6) and 78% (n=6). Using pair t- test analysis, decrease in TTP time was stastistically significant pre and post treatment (p < 0.01). Conclusion: With the significant changes in blood flow parameter pre and post treatment as well as improvement of the gain percentage blood flow time, syngo iFlow application can be the first marker to determine the successful rate of the revascularization technique objectively. 2018 Thesis http://eprints.usm.my/46464/ http://eprints.usm.my/46464/1/Dr.%20Mohd%20Helmi%20Hamzah-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC666-701 Diseases of the circulatory (Cardiovascular) system
spellingShingle	RC666-701 Diseases of the circulatory (Cardiovascular) system Hamzah, Mohd Helmi Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
description	Background: Digital subtraction angiography (DSA) remains the gold standard in diagnosing complicated peripheral vascular disease and is the only imaging modality capable of visualizing endovascular treatments in all contexts. The purpose of the study is determine the means different of arterial flow time (FT) of DSA on the lower limb circulation pre and post successful revascularization using time density curve (TDC) on syngo iFlow application. Methodology: A total of 45 patients, retrospectively review the pre and post successful revascularization blood flow time using syngo iFlow application. The blood flow time (TTP) of the successful arterial flow is determined by using the application. Mean and SDs were obtained for each measurement, and level of significance for pre and post treatment was studied (P < 0.05). Result: In total of 45 subject was studied (26 male, 19 female, means age 59.3). Stenoses were graded as follows based on the angiographic finding: less than 50% stenosis 2 patients; 50-75% stenosis 37patients; 76-99%, 6 patients. There was a significant difference in means between proximal and distal stenosis for pre treatment (p-value<0.001). The mean difference of pre treatment was -0.84 with mean(SD) for pre and post stenotic segment were 3.94s(0.43) and 4.78s(0.80) respectively. There was also significant mean difference between proximal and distal stenosis for post treatment ( p-value<0.001). The mean difference of post treatment was -0.34 with mean(SD) for pre and post stenotic segment were 3.90s(0.39) and 4.16s(0.52) respectively. Before treatment, means TTP time (time to peak time) between contrast time curve proximal and distal to the treated vessels segment was 3.94s and 4.78s respectively, after treatment was 3.90s and 4.156s respectively. Gain percentage of the improvement time was highest at 62% (n=10), second most 83% (n=6) and 78% (n=6). Using pair t- test analysis, decrease in TTP time was stastistically significant pre and post treatment (p < 0.01). Conclusion: With the significant changes in blood flow parameter pre and post treatment as well as improvement of the gain percentage blood flow time, syngo iFlow application can be the first marker to determine the successful rate of the revascularization technique objectively.
format	Thesis
qualification_level	Master's degree
author	Hamzah, Mohd Helmi
author_facet	Hamzah, Mohd Helmi
author_sort	Hamzah, Mohd Helmi
title	Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
title_short	Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
title_full	Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
title_fullStr	Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
title_full_unstemmed	Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)
title_sort	quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iflow)
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2018
url	http://eprints.usm.my/46464/1/Dr.%20Mohd%20Helmi%20Hamzah-24%20pages.pdf
_version_	1747821676885704704

Quantitative assessment of the lower limb digital subtraction angiography post successful revascularization using optical flow method (syngo iFlow)

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