Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI

Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Meth...

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Main Author:	Kamarudin, Mohd Nazlin
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RC Internal medicine
Online Access:	http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf
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spelling	my-usm-ep.465042020-03-16T07:53:39Z Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI 2018 Kamarudin, Mohd Nazlin RC Internal medicine Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Methodology: 38 healthy volunteers were included in this prospective study. Diffusion tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging sequences in 16 and 32 diffusion directions. Three different b-values were selected for each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise ratio (SNR) was measured in each muscle at different b-values and number of diffusion direction, and average SNR were calculated. Statistical analysis was performed with one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each DTI parameters, and level of significance was determined (p < 0.05). Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2 (subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had shown to improve SNR value compared to 16 diffusion directions (P<0.05). Conclusions: The optimal combination of b value and number of diffusion directions in DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions respectively. 2018 Thesis http://eprints.usm.my/46504/ http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Kamarudin, Mohd Nazlin Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
description	Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Methodology: 38 healthy volunteers were included in this prospective study. Diffusion tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging sequences in 16 and 32 diffusion directions. Three different b-values were selected for each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise ratio (SNR) was measured in each muscle at different b-values and number of diffusion direction, and average SNR were calculated. Statistical analysis was performed with one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each DTI parameters, and level of significance was determined (p < 0.05). Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2 (subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had shown to improve SNR value compared to 16 diffusion directions (P<0.05). Conclusions: The optimal combination of b value and number of diffusion directions in DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions respectively.
format	Thesis
qualification_level	Master's degree
author	Kamarudin, Mohd Nazlin
author_facet	Kamarudin, Mohd Nazlin
author_sort	Kamarudin, Mohd Nazlin
title	Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_short	Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_full	Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_fullStr	Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_full_unstemmed	Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_sort	diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 tesla mri
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2018
url	http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf
_version_	1747821684463763456

Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI

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