Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application

This work presents the fabrication of scaffold by using freeze extraction method and cotton candy machine for application vascular tissue engineering. The single layer scaffold by cotton candy machine was studied on different polylactic acid (PLA) annealing time for 24 hours, 48 hours and 72 hours i...

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Main Author:	Aziz, Nazatul Shafiqah Abdul
Format:	Thesis
Language:	English
Published:	2019
Subjects:	T Technology
Online Access:	http://eprints.usm.my/46751/1/Cotton%20Candy%20Machine%20Explore%20Its%20Potential%20For%20Fabrication%20Of%20Polymer%20Microfiber%20For%20Vascular%20Tissue%20Engineering%20Application.pdf
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spelling	my-usm-ep.467512021-11-17T03:42:11Z Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application 2019-08-01 Aziz, Nazatul Shafiqah Abdul T Technology TA401-492 Materials of engineering and construction. Mechanics of materials This work presents the fabrication of scaffold by using freeze extraction method and cotton candy machine for application vascular tissue engineering. The single layer scaffold by cotton candy machine was studied on different polylactic acid (PLA) annealing time for 24 hours, 48 hours and 72 hours in 80°C to analyse the optimize single layer scaffold. The single layer scaffold in different concentrations 3 wt%, 6 wt%, and 9 wt% of poly(L-lactic acid-co-ε-caprolactone) (PLCL) produced by using freeze extraction method was investigated. The combination of boths method were produced to form double and multilayer scaffold. The ideal scaffold was fabricated to form tissue scaffold that similar to the native cardiovascular tissue. The morphological changes in different concentrations PLCL and PLA annealing time were observed via scanning electron microscope (SEM) with porosity varied from 21 % to 32 % for PLA scaffold with different annealing time of PLA and 19 % to 43 % for different concentrations of PLCL. The 72 hours of the PLA annealed time were smaller diameter and smaller pore size. The 9 wt% of concentration PLCL was optimum single scaffold by freeze extraction method due to the largest pore size forms compare to others. The double layer scaffold were shows that, it is suitable to form scaffold compared to the multilayer scaffold due to the formation of gap between layer. 2019-08 Thesis http://eprints.usm.my/46751/ http://eprints.usm.my/46751/1/Cotton%20Candy%20Machine%20Explore%20Its%20Potential%20For%20Fabrication%20Of%20Polymer%20Microfiber%20For%20Vascular%20Tissue%20Engineering%20Application.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Kejuruteraan Bahan & Sumber Mineral
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T Technology T Technology
spellingShingle	T Technology T Technology Aziz, Nazatul Shafiqah Abdul Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
description	This work presents the fabrication of scaffold by using freeze extraction method and cotton candy machine for application vascular tissue engineering. The single layer scaffold by cotton candy machine was studied on different polylactic acid (PLA) annealing time for 24 hours, 48 hours and 72 hours in 80°C to analyse the optimize single layer scaffold. The single layer scaffold in different concentrations 3 wt%, 6 wt%, and 9 wt% of poly(L-lactic acid-co-ε-caprolactone) (PLCL) produced by using freeze extraction method was investigated. The combination of boths method were produced to form double and multilayer scaffold. The ideal scaffold was fabricated to form tissue scaffold that similar to the native cardiovascular tissue. The morphological changes in different concentrations PLCL and PLA annealing time were observed via scanning electron microscope (SEM) with porosity varied from 21 % to 32 % for PLA scaffold with different annealing time of PLA and 19 % to 43 % for different concentrations of PLCL. The 72 hours of the PLA annealed time were smaller diameter and smaller pore size. The 9 wt% of concentration PLCL was optimum single scaffold by freeze extraction method due to the largest pore size forms compare to others. The double layer scaffold were shows that, it is suitable to form scaffold compared to the multilayer scaffold due to the formation of gap between layer.
format	Thesis
qualification_level	Master's degree
author	Aziz, Nazatul Shafiqah Abdul
author_facet	Aziz, Nazatul Shafiqah Abdul
author_sort	Aziz, Nazatul Shafiqah Abdul
title	Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
title_short	Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
title_full	Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
title_fullStr	Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
title_full_unstemmed	Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application
title_sort	cotton candy machine explore its potential for fabrication of polymer microfiber for vascular tissue engineering application
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Kejuruteraan Bahan & Sumber Mineral
publishDate	2019
url	http://eprints.usm.my/46751/1/Cotton%20Candy%20Machine%20Explore%20Its%20Potential%20For%20Fabrication%20Of%20Polymer%20Microfiber%20For%20Vascular%20Tissue%20Engineering%20Application.pdf
_version_	1747821722878345216

Cotton Candy Machine Explore Its Potential For Fabrication Of Polymer Microfiber For Vascular Tissue Engineering Application

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