In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus

The in vitro α-glucosidase inhibitory and antioxidant activities, total phenolic and vitamin C contents of the pure juices (squeezed from the pulps), peel and pulp extracts from siix Citrus fruits that are grown in Malaysia, which are Citrus aurantifolia, Citrus grandis var. Tambun (PO52) and var. P...

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Main Author:	Henrietta, Ikwunne Helen
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/47499/1/IKWUNNE%20HELEN%20HENRIETTA%20-%20IN%20VITRO%20ANTIOXIDANT%20AND%20ALPHAGLUCOSIDASE%20INHIBITORY%20ACTIVITIES%20OF.pdf
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spelling	my-usm-ep.474992020-10-12T07:18:42Z In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus 2018-08 Henrietta, Ikwunne Helen RS1-441 Pharmacy and materia medica The in vitro α-glucosidase inhibitory and antioxidant activities, total phenolic and vitamin C contents of the pure juices (squeezed from the pulps), peel and pulp extracts from siix Citrus fruits that are grown in Malaysia, which are Citrus aurantifolia, Citrus grandis var. Tambun (PO52) and var. Penang Merah (PO5), Citrus hystrix, Citrus latifolia, and Citrus madurensis together with Citrus limon from Spain were determined in this comparative study. This is owing to the fact that these Citrus species that can be found in Malaysia has never been comparatively studied. The peels are mostly studied while the pulps and the juices are given less attention. The fresh and dried peel and pulp samples were extracted using methanol, ethanol and distilled water while 80% methanol was used for the extraction of crude extracts from dried peels and pulps. The result obtained from 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay revealed the highest free radical scavenging activity (96.14 ± 0.30%) of the methanol extract of dried peel of C. limon (at 100 mg/mL). The methanol extract of dried peel (at 100 mg/mL) and the juice of C. grandis var. Tambun (PO52) shared the highest ferric-reducing antioxidant power (FRAP) at 85.03 ± 6.32% and 84.29 ± 0.40%, respectively. The ethanol extract of fresh peel of C. grandis var. Penang Merah (PO5) exhibited the highest metal chelating activity at 98.85 ± 0.82%. Among the juices, the juice of C. grandis var. Tambun (PO52) gave the highest total phenolic content (TPC) of 14956.34± 152.65 μg gallic acid equivalent (GAE)/g juice. The distilled water extract of dried peel of C. limon gave the highest TPC at 33148.87 ± 124.46 μg GAE/g fresh weight of sample. 2018-08 Thesis http://eprints.usm.my/47499/ http://eprints.usm.my/47499/1/IKWUNNE%20HELEN%20HENRIETTA%20-%20IN%20VITRO%20ANTIOXIDANT%20AND%20ALPHAGLUCOSIDASE%20INHIBITORY%20ACTIVITIES%20OF.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Henrietta, Ikwunne Helen In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
description	The in vitro α-glucosidase inhibitory and antioxidant activities, total phenolic and vitamin C contents of the pure juices (squeezed from the pulps), peel and pulp extracts from siix Citrus fruits that are grown in Malaysia, which are Citrus aurantifolia, Citrus grandis var. Tambun (PO52) and var. Penang Merah (PO5), Citrus hystrix, Citrus latifolia, and Citrus madurensis together with Citrus limon from Spain were determined in this comparative study. This is owing to the fact that these Citrus species that can be found in Malaysia has never been comparatively studied. The peels are mostly studied while the pulps and the juices are given less attention. The fresh and dried peel and pulp samples were extracted using methanol, ethanol and distilled water while 80% methanol was used for the extraction of crude extracts from dried peels and pulps. The result obtained from 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay revealed the highest free radical scavenging activity (96.14 ± 0.30%) of the methanol extract of dried peel of C. limon (at 100 mg/mL). The methanol extract of dried peel (at 100 mg/mL) and the juice of C. grandis var. Tambun (PO52) shared the highest ferric-reducing antioxidant power (FRAP) at 85.03 ± 6.32% and 84.29 ± 0.40%, respectively. The ethanol extract of fresh peel of C. grandis var. Penang Merah (PO5) exhibited the highest metal chelating activity at 98.85 ± 0.82%. Among the juices, the juice of C. grandis var. Tambun (PO52) gave the highest total phenolic content (TPC) of 14956.34± 152.65 μg gallic acid equivalent (GAE)/g juice. The distilled water extract of dried peel of C. limon gave the highest TPC at 33148.87 ± 124.46 μg GAE/g fresh weight of sample.
format	Thesis
qualification_level	Master's degree
author	Henrietta, Ikwunne Helen
author_facet	Henrietta, Ikwunne Helen
author_sort	Henrietta, Ikwunne Helen
title	In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
title_short	In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
title_full	In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
title_fullStr	In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
title_full_unstemmed	In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
title_sort	in vitro antioxidant and alpha-glucosidase inhibitory activities of fruit extracts from seven species of citrus
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2018
url	http://eprints.usm.my/47499/1/IKWUNNE%20HELEN%20HENRIETTA%20-%20IN%20VITRO%20ANTIOXIDANT%20AND%20ALPHAGLUCOSIDASE%20INHIBITORY%20ACTIVITIES%20OF.pdf
_version_	1747821790429708288

In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus

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