Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231

Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231

The present study was conducted with the objective to study the anti-cancer property of red onion (Allium cepa) peel extracts and its fractions by investigating the effects in MDA-MB-231, MCF-7 and Cal-27. The effects of red onion peel extracts and its fractions in the anti-proliferative activity, i...

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Main Author: Siah, Poh Chiew
Format: Thesis
Language:English
Published: 2017
Subjects:
QK495 Angiosperms
Online Access:http://eprints.usm.my/47773/1/EFFECT%20OF%20RED%20ONION%20%28Allium%20cepa%29%20PEEL.pdf%20cut.pdf
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spelling my-usm-ep.477732020-10-26T07:17:20Z Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231 2017-11 Siah, Poh Chiew QK495 Angiosperms The present study was conducted with the objective to study the anti-cancer property of red onion (Allium cepa) peel extracts and its fractions by investigating the effects in MDA-MB-231, MCF-7 and Cal-27. The effects of red onion peel extracts and its fractions in the anti-proliferative activity, induction of apoptosis - programmed cell death and anti-metastasis were studied. In addition, the involvement of Wnt signalling pathway in the anti-cancer activity of red onion peel extracts and its fractions was also investigated. In the results, the extracts (E1 and E3) and fractions (F1, F2, F1W and F2W) showed promising inhibitory effect on cell viability of MDA-MB-231. 2017-11 Thesis http://eprints.usm.my/47773/ http://eprints.usm.my/47773/1/EFFECT%20OF%20RED%20ONION%20%28Allium%20cepa%29%20PEEL.pdf%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORM)
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic QK495 Angiosperms
spellingShingle QK495 Angiosperms
Siah, Poh Chiew
Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
description The present study was conducted with the objective to study the anti-cancer property of red onion (Allium cepa) peel extracts and its fractions by investigating the effects in MDA-MB-231, MCF-7 and Cal-27. The effects of red onion peel extracts and its fractions in the anti-proliferative activity, induction of apoptosis - programmed cell death and anti-metastasis were studied. In addition, the involvement of Wnt signalling pathway in the anti-cancer activity of red onion peel extracts and its fractions was also investigated. In the results, the extracts (E1 and E3) and fractions (F1, F2, F1W and F2W) showed promising inhibitory effect on cell viability of MDA-MB-231.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Siah, Poh Chiew
author_facet Siah, Poh Chiew
author_sort Siah, Poh Chiew
title Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
title_short Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
title_full Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
title_fullStr Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
title_full_unstemmed Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
title_sort effect of red onion (allium cepa) peel extracts and fractions on cell proliferative and metastatic activities in mda-mb-231
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORM)
publishDate 2017
url http://eprints.usm.my/47773/1/EFFECT%20OF%20RED%20ONION%20%28Allium%20cepa%29%20PEEL.pdf%20cut.pdf
_version_ 1747821828503502848

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