Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain

Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling a...

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Main Author:	Yahaya, Raden Nezarul Raden
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RD Surgery
Online Access:	http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf
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spelling	my-usm-ep.478462020-11-03T08:22:26Z Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain 2018 Yahaya, Raden Nezarul Raden RD Surgery Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling and received intravenous preparation of fentanyl citrate at dose of 4 mcg/kg administered through oxygen driven nebulizer circuit. Pain scores were assessed at pre-treatment and subsequently at 5 minutes interval until 60 minutes post-treatment using Wong and Baker faces pain scale. Vital signs and potential adverse events were also monitored. Results: 42 children with acute pain of various causes participated in this study and tolerated the nebulized fentanyl citrate well. 2 patients were withdrawn due to insufficient pain control post treatment. The pain aetiologies were categorized into fractures (n=14), soft tissue injuries (n=15) and abdominal pain (n=11). The mean pain score at 10 minutes on nebulized fentanyl administration decreased by 2.65 (95% CI 2.62 to 2.73) from the baseline. Pain score continued to decrease at 15 minutes (mean pain score difference 4.20; 95% CI 4.01 to 4.39) followed by a sustained plateau pain score at 20 minutes until 60 minutes. The pain score reduction at alltime intervals measured post-treatment were highly significant (P <0.001). No adverse events or vital signs deterioration observed following nebulized fentanyl. Conclusion: Nebulized fentanyl citrate at dose of 4 mcg/kg given through oxygen drive nebulizer circuit was effective in treating children with acute severe pain without causing adverse events and should be considered as a modality of acute pain treatment in children population. 2018 Thesis http://eprints.usm.my/47846/ http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RD Surgery
spellingShingle	RD Surgery Yahaya, Raden Nezarul Raden Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
description	Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling and received intravenous preparation of fentanyl citrate at dose of 4 mcg/kg administered through oxygen driven nebulizer circuit. Pain scores were assessed at pre-treatment and subsequently at 5 minutes interval until 60 minutes post-treatment using Wong and Baker faces pain scale. Vital signs and potential adverse events were also monitored. Results: 42 children with acute pain of various causes participated in this study and tolerated the nebulized fentanyl citrate well. 2 patients were withdrawn due to insufficient pain control post treatment. The pain aetiologies were categorized into fractures (n=14), soft tissue injuries (n=15) and abdominal pain (n=11). The mean pain score at 10 minutes on nebulized fentanyl administration decreased by 2.65 (95% CI 2.62 to 2.73) from the baseline. Pain score continued to decrease at 15 minutes (mean pain score difference 4.20; 95% CI 4.01 to 4.39) followed by a sustained plateau pain score at 20 minutes until 60 minutes. The pain score reduction at alltime intervals measured post-treatment were highly significant (P <0.001). No adverse events or vital signs deterioration observed following nebulized fentanyl. Conclusion: Nebulized fentanyl citrate at dose of 4 mcg/kg given through oxygen drive nebulizer circuit was effective in treating children with acute severe pain without causing adverse events and should be considered as a modality of acute pain treatment in children population.
format	Thesis
qualification_level	Master's degree
author	Yahaya, Raden Nezarul Raden
author_facet	Yahaya, Raden Nezarul Raden
author_sort	Yahaya, Raden Nezarul Raden
title	Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_short	Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_full	Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_fullStr	Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_full_unstemmed	Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_sort	study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2018
url	http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf
_version_	1747821839743188992

Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain

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