Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts

In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereski...

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Main Author:	Ch’ng, Yung Sing
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf
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id	my-usm-ep.48045
record_format	uketd_dc
spelling	my-usm-ep.480452021-01-04T01:55:45Z Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts 2017-11 Ch’ng, Yung Sing RS1-441 Pharmacy and materia medica In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King seeds were selected and their extracts (water extracts, 50% ethanol extracts, and 95 % ethanol extracts) underwent preliminary testing to screen for their antihypertensive activities and their vasorelaxation. The results showed that the seeds of Swietenia macrophylla King has the highest potential in vasorelaxation, followed by Vernonia amygdalina. This study found that, crude VAE and SM50, which contain multiple chemical components, exhibited a stronger vasorelaxant effect on isolated aortic rings due to their possible involvement of multiple mechanisms. 2017-11 Thesis http://eprints.usm.my/48045/ http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi (School of Pharmacy)
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Ch’ng, Yung Sing Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
description	In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King seeds were selected and their extracts (water extracts, 50% ethanol extracts, and 95 % ethanol extracts) underwent preliminary testing to screen for their antihypertensive activities and their vasorelaxation. The results showed that the seeds of Swietenia macrophylla King has the highest potential in vasorelaxation, followed by Vernonia amygdalina. This study found that, crude VAE and SM50, which contain multiple chemical components, exhibited a stronger vasorelaxant effect on isolated aortic rings due to their possible involvement of multiple mechanisms.
format	Thesis
qualification_level	Master's degree
author	Ch’ng, Yung Sing
author_facet	Ch’ng, Yung Sing
author_sort	Ch’ng, Yung Sing
title	Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
title_short	Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
title_full	Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
title_fullStr	Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
title_full_unstemmed	Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
title_sort	antihypertensive and vasodilatory effects of vernonia amygdalina and swietenia macrophylla extracts
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi (School of Pharmacy)
publishDate	2017
url	http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf
_version_	1747821871753068544

Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts

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