Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers

This research aimed to evaluate the prevalence of anemia, effectiveness of drug regimens, factors contributing to the control of hemoglobin levels, and factors contributing to cardiovascular events, hospitalizations, deaths, as well as, the annual direct medical costs of anemia treatment at governme...

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Main Author:	Farag, Omalhassan Amir Abdelkarim
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/48055/1/EVALUATION%20OF%20CLINICAL%20OUTCOMES%20AND.pdf%20cut.pdf
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spelling	my-usm-ep.480552021-01-08T01:55:21Z Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers 2017-11 Farag, Omalhassan Amir Abdelkarim RS1-441 Pharmacy and materia medica This research aimed to evaluate the prevalence of anemia, effectiveness of drug regimens, factors contributing to the control of hemoglobin levels, and factors contributing to cardiovascular events, hospitalizations, deaths, as well as, the annual direct medical costs of anemia treatment at government hemodialysis centers in Khartoum State, Sudan. This research was an observational prospective longitudinal study where all patients at the 12 dialysis centers were followed from August 2012 to July 2013. A total of 1015 patients were recruited in this study. Out of these, 194 (19.1%) patients were transferred to other centers, 165 (16.3%) died, 84 (8.3%) were lost during follow-up, and 38 (3.7%) underwent renal transplantation. A total of 534 (52.6%) patients completed the study and were included in the analysis. The majorities were males 307 (57.5%), the age ranged from 18-85 years, mean age was 48.7±16.1 years, and the median age was 50 years. The study found anemia in all the patients, hemoglobin level (<12 g/dL), whereas about 67% had a hemoglobin level <10 g/dL and only 20% had achieved the target Hb level (≥12 g/dL) in the last month. However, a significant improvement in mean Hb levels in seven drug regimens was found. Approximately 61% of patients received erythropoietin-stimulating agents (ESAs), and 87.1% received iron dextran. The most frequent anemia drugs regimen were 'ESA, intravenous (IV) iron, oral iron and vitamins (vitamin B12 and folic acid)' for 39.5% of the patients. Only 27% of the patients were tested for ferritin and transferrin saturation. 2017-11 Thesis http://eprints.usm.my/48055/ http://eprints.usm.my/48055/1/EVALUATION%20OF%20CLINICAL%20OUTCOMES%20AND.pdf%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi (School of Pharmacy)
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Farag, Omalhassan Amir Abdelkarim Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
description	This research aimed to evaluate the prevalence of anemia, effectiveness of drug regimens, factors contributing to the control of hemoglobin levels, and factors contributing to cardiovascular events, hospitalizations, deaths, as well as, the annual direct medical costs of anemia treatment at government hemodialysis centers in Khartoum State, Sudan. This research was an observational prospective longitudinal study where all patients at the 12 dialysis centers were followed from August 2012 to July 2013. A total of 1015 patients were recruited in this study. Out of these, 194 (19.1%) patients were transferred to other centers, 165 (16.3%) died, 84 (8.3%) were lost during follow-up, and 38 (3.7%) underwent renal transplantation. A total of 534 (52.6%) patients completed the study and were included in the analysis. The majorities were males 307 (57.5%), the age ranged from 18-85 years, mean age was 48.7±16.1 years, and the median age was 50 years. The study found anemia in all the patients, hemoglobin level (<12 g/dL), whereas about 67% had a hemoglobin level <10 g/dL and only 20% had achieved the target Hb level (≥12 g/dL) in the last month. However, a significant improvement in mean Hb levels in seven drug regimens was found. Approximately 61% of patients received erythropoietin-stimulating agents (ESAs), and 87.1% received iron dextran. The most frequent anemia drugs regimen were 'ESA, intravenous (IV) iron, oral iron and vitamins (vitamin B12 and folic acid)' for 39.5% of the patients. Only 27% of the patients were tested for ferritin and transferrin saturation.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Farag, Omalhassan Amir Abdelkarim
author_facet	Farag, Omalhassan Amir Abdelkarim
author_sort	Farag, Omalhassan Amir Abdelkarim
title	Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
title_short	Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
title_full	Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
title_fullStr	Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
title_full_unstemmed	Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers
title_sort	evaluation of clinical outcomes and direct medical cost of anemia management among end stage renal disease patients in khartoum state hemodialysis centers
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi (School of Pharmacy)
publishDate	2017
url	http://eprints.usm.my/48055/1/EVALUATION%20OF%20CLINICAL%20OUTCOMES%20AND.pdf%20cut.pdf
_version_	1747821873446518784

Evaluation Of Clinical Outcomes And Direct Medical Cost Of Anemia Management Among End Stage Renal Disease Patients In Khartoum State Hemodialysis Centers

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