Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet

In the development of orally disintegrating tablets (ODT), palatability plays a critical role. As there were hardly any reported studies on taste masking of drugs which cause burning sensation on oral mucosa and is bitter in taste, dapoxetine HCl was chosen for the study. Various taste masking techn...

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Main Author: Liew, Kai Bin
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://eprints.usm.my/48065/1/INVESTIGATION%20OF%20TASTE%20MASKING.pdf%20cut.pdf
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spelling my-usm-ep.480652021-01-11T02:42:17Z Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet 2017-11 Liew, Kai Bin RS1-441 Pharmacy and materia medica In the development of orally disintegrating tablets (ODT), palatability plays a critical role. As there were hardly any reported studies on taste masking of drugs which cause burning sensation on oral mucosa and is bitter in taste, dapoxetine HCl was chosen for the study. Various taste masking techniques, namely complex formation with ion exchange resin, coating with pH sensitive polymer, coating with hydrophilic polymer, chemical modification, addition of sweetener and flavour, inclusion complexation and blending with inorganic compound, were investigated. 2017-11 Thesis http://eprints.usm.my/48065/ http://eprints.usm.my/48065/1/INVESTIGATION%20OF%20TASTE%20MASKING.pdf%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi (School of Pharmacy)
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Liew, Kai Bin
Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
description In the development of orally disintegrating tablets (ODT), palatability plays a critical role. As there were hardly any reported studies on taste masking of drugs which cause burning sensation on oral mucosa and is bitter in taste, dapoxetine HCl was chosen for the study. Various taste masking techniques, namely complex formation with ion exchange resin, coating with pH sensitive polymer, coating with hydrophilic polymer, chemical modification, addition of sweetener and flavour, inclusion complexation and blending with inorganic compound, were investigated.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Liew, Kai Bin
author_facet Liew, Kai Bin
author_sort Liew, Kai Bin
title Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
title_short Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
title_full Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
title_fullStr Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
title_full_unstemmed Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet
title_sort investigation of taste masking techniques and development of dapoxetine hcl orally disintegrating tablet
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi (School of Pharmacy)
publishDate 2017
url http://eprints.usm.my/48065/1/INVESTIGATION%20OF%20TASTE%20MASKING.pdf%20cut.pdf
_version_ 1747821874906136576