A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida

Introduction: Southeast Asian ovalocytosis (SAO) and iron deficiency anaemia (IDA) are common in Malaysia. Both have specific red blood cells (RBC) parameters pattern but overlapping morphological features. When SAO patients having concomitant IDA, it is quite challenging to differentiate them. Thus...

Full description

Saved in:

Bibliographic Details
Main Author:	Ghazali, Nik Shaida Shamim Nik
Format:	Thesis
Language:	English
Published:	2019
Subjects:	RZ Other systems of medicine
Online Access:	http://eprints.usm.my/48147/1/NIK%20SHAIDA%20SHAMIM%20BINTI%20NIK%20GHAZALI_hj.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.48147
record_format	uketd_dc
spelling	my-usm-ep.481472021-01-20T07:42:00Z A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida 2019 Ghazali, Nik Shaida Shamim Nik RZ Other systems of medicine Introduction: Southeast Asian ovalocytosis (SAO) and iron deficiency anaemia (IDA) are common in Malaysia. Both have specific red blood cells (RBC) parameters pattern but overlapping morphological features. When SAO patients having concomitant IDA, it is quite challenging to differentiate them. Thus, the study aims to study RBC parameters in three groups of individuals with SAO alone, IDA alone and SAO with concomitant IDA and identifying potential parameters in discriminating them. Methodology: A retrospective cross-sectional study was conducted among 79 subjects from Institut Perubatan dan Pergigian (IPPT), USM (30 cases with SAO alone and IDA alone and 19 cases SAO with IDA). The data were obtained from the laboratory information system (LIS) of Advanced Diagnostic Laboratory from January 2010 to May 2019. Univariable analysis (One-way ANOVA or Kruskal-Wallis test) was used to compare the red blood cell parameters between the three groups, which include RBC, Hb, MCV, MCH, MCHC and RDW. Statistical significance was set at a P-value of <0.05. Results: SAO with concomitant IDA showed mean of RBC, Hb, MCV, MCH, MCHC and RDW of 3.5 x 106/μL, 9.2 g/dL, 74.6 fL, 25.7 pg, 33.7 g/dL and 46.0 fL, respectively. It was found that the Hb, MCV and MCH of SAO with concomitant IDA group were lower compared to the SAO alone group with significance P-value (P<0.001). However, the RBC count, MCHC and RDW parameters were not significant between both groups (P>0.05). 2019 Thesis http://eprints.usm.my/48147/ http://eprints.usm.my/48147/1/NIK%20SHAIDA%20SHAMIM%20BINTI%20NIK%20GHAZALI_hj.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RZ Other systems of medicine
spellingShingle	RZ Other systems of medicine Ghazali, Nik Shaida Shamim Nik A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
description	Introduction: Southeast Asian ovalocytosis (SAO) and iron deficiency anaemia (IDA) are common in Malaysia. Both have specific red blood cells (RBC) parameters pattern but overlapping morphological features. When SAO patients having concomitant IDA, it is quite challenging to differentiate them. Thus, the study aims to study RBC parameters in three groups of individuals with SAO alone, IDA alone and SAO with concomitant IDA and identifying potential parameters in discriminating them. Methodology: A retrospective cross-sectional study was conducted among 79 subjects from Institut Perubatan dan Pergigian (IPPT), USM (30 cases with SAO alone and IDA alone and 19 cases SAO with IDA). The data were obtained from the laboratory information system (LIS) of Advanced Diagnostic Laboratory from January 2010 to May 2019. Univariable analysis (One-way ANOVA or Kruskal-Wallis test) was used to compare the red blood cell parameters between the three groups, which include RBC, Hb, MCV, MCH, MCHC and RDW. Statistical significance was set at a P-value of <0.05. Results: SAO with concomitant IDA showed mean of RBC, Hb, MCV, MCH, MCHC and RDW of 3.5 x 106/μL, 9.2 g/dL, 74.6 fL, 25.7 pg, 33.7 g/dL and 46.0 fL, respectively. It was found that the Hb, MCV and MCH of SAO with concomitant IDA group were lower compared to the SAO alone group with significance P-value (P<0.001). However, the RBC count, MCHC and RDW parameters were not significant between both groups (P>0.05).
format	Thesis
qualification_level	Master's degree
author	Ghazali, Nik Shaida Shamim Nik
author_facet	Ghazali, Nik Shaida Shamim Nik
author_sort	Ghazali, Nik Shaida Shamim Nik
title	A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
title_short	A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
title_full	A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
title_fullStr	A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
title_full_unstemmed	A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida
title_sort	comparison study of red blood cell indices in southeast asian ovalocytosis (sao), iron deficiency anaemia (ida) and sao with concomitant ida
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2019
url	http://eprints.usm.my/48147/1/NIK%20SHAIDA%20SHAMIM%20BINTI%20NIK%20GHAZALI_hj.pdf
_version_	1747821888593199104

A Comparison Study Of Red Blood Cell Indices In Southeast Asian Ovalocytosis (Sao), Iron Deficiency Anaemia (Ida) And Sao With Concomitant Ida

Similar Items