Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation

Microorganisms provide plenty of natural pigments as a safe alternative to the synthetic dyes in many industrial applications including cosmetics, food, textile, pharmaceutical and aquaculture industries. This research was aimed to study the natural red pigment prodigiosin with antimicrobial activit...

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Main Author:	Nazari, Teh Faridah
Format:	Thesis
Language:	English
Published:	2018
Subjects:	T175-178 Industrial research Research and development
Online Access:	http://eprints.usm.my/48262/1/TEH%20FARIDAH%20BINTI%20NAZARI%20_hj.pdf
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id	my-usm-ep.48262
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spelling	my-usm-ep.482622021-02-08T07:31:32Z Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation 2018-09 Nazari, Teh Faridah T175-178 Industrial research. Research and development Microorganisms provide plenty of natural pigments as a safe alternative to the synthetic dyes in many industrial applications including cosmetics, food, textile, pharmaceutical and aquaculture industries. This research was aimed to study the natural red pigment prodigiosin with antimicrobial activity of a marine bacterium. The finding of natural colorant with antimicrobial activity can give benefits to many industries and acts as a natural coloring agent with preservative value simultaneously to the industrial products. In this study, Serratia marcescens IBRL USM84 was isolated from a local marine sponge Xetospongia testudinaria from Pulau Bidong, Terengganu. The analysis of antimicrobial activity from intracellular and extracellular pigments was performed and found that the antimicrobial activity from intracellular pigment was greater. The analysis of pigment production revealed that intracellularly and extracellularly extracted pigments were able to produce different color intensity at different quantity, where the pigment from intracellular yielded 7.02 g/L compared to extracellular pigment that was 0.25 g/L only. From the enhancement process, S. marcescens IBRL USM84 produced higher prodigiosin pigment and better antibacterial activity after 48 hours of cultivation period with medium initial pH at 7, incubated at 25oC and with 150 rpm of agitation speed, the addition with 0.2 % of agar and 1% of maltose under light condition. The dichloromethane extract from intracellular pigment produced by S. marcescens IBRL USM84 showed higher pigmentation strength with greater antimicrobial activity compared to other extracts. 2018-09 Thesis http://eprints.usm.my/48262/ http://eprints.usm.my/48262/1/TEH%20FARIDAH%20BINTI%20NAZARI%20_hj.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Kajihayat
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T175-178 Industrial research Research and development
spellingShingle	T175-178 Industrial research Research and development Nazari, Teh Faridah Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
description	Microorganisms provide plenty of natural pigments as a safe alternative to the synthetic dyes in many industrial applications including cosmetics, food, textile, pharmaceutical and aquaculture industries. This research was aimed to study the natural red pigment prodigiosin with antimicrobial activity of a marine bacterium. The finding of natural colorant with antimicrobial activity can give benefits to many industries and acts as a natural coloring agent with preservative value simultaneously to the industrial products. In this study, Serratia marcescens IBRL USM84 was isolated from a local marine sponge Xetospongia testudinaria from Pulau Bidong, Terengganu. The analysis of antimicrobial activity from intracellular and extracellular pigments was performed and found that the antimicrobial activity from intracellular pigment was greater. The analysis of pigment production revealed that intracellularly and extracellularly extracted pigments were able to produce different color intensity at different quantity, where the pigment from intracellular yielded 7.02 g/L compared to extracellular pigment that was 0.25 g/L only. From the enhancement process, S. marcescens IBRL USM84 produced higher prodigiosin pigment and better antibacterial activity after 48 hours of cultivation period with medium initial pH at 7, incubated at 25oC and with 150 rpm of agitation speed, the addition with 0.2 % of agar and 1% of maltose under light condition. The dichloromethane extract from intracellular pigment produced by S. marcescens IBRL USM84 showed higher pigmentation strength with greater antimicrobial activity compared to other extracts.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Nazari, Teh Faridah
author_facet	Nazari, Teh Faridah
author_sort	Nazari, Teh Faridah
title	Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
title_short	Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
title_full	Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
title_fullStr	Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
title_full_unstemmed	Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation
title_sort	production of prodigiosin by serratia marcescens ibrl usm84 for lipstick formulation
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kajihayat
publishDate	2018
url	http://eprints.usm.my/48262/1/TEH%20FARIDAH%20BINTI%20NAZARI%20_hj.pdf
_version_	1747821911649288192

Production Of Prodigiosin By Serratia Marcescens Ibrl Usm84 For Lipstick Formulation

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