The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.

OBJECTIVES: The objectives of this study were to detennine prevalence and associated factors of intracranial lesions on :MRI examination and the accuracy of FLAIR in detecting intracranial lesions in patients with headache but no neurological deficit. METHOD: A retrospective and prospective cross...

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Main Author:	Jaafar, Wan Daizyreena Wan
Format:	Thesis
Language:	English
Published:	2007
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/48436/1/DR%20WAN%20DAIZYREENA%20BINTI%20WAN%20JAAFAR.pdf
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id	my-usm-ep.48436
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spelling	my-usm-ep.484362021-02-24T07:07:40Z The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit. 2007 Jaafar, Wan Daizyreena Wan R Medicine (General) OBJECTIVES: The objectives of this study were to detennine prevalence and associated factors of intracranial lesions on :MRI examination and the accuracy of FLAIR in detecting intracranial lesions in patients with headache but no neurological deficit. METHOD: A retrospective and prospective cross-sectional study was perfonned over 51 months from 1 st June 2002 until 30th September 2006. One hundred and forty-three patients with headache but no neurological deficit aged 13 years old and above who had underwent routine :MRI examination of brain in Hospital University Sains Malaysia were included into this study. For each case, FLAIR sequence and complete brain series were reviewed separately at different times by two radiologists. RESULTS: Prevalence of intracranial lesions on complete MRI sequence was 18.9% (95% CI: 0.06, 0.32). The sensitivity for FLAIR was 92.6% and the specificity of 92.2%. Age more than 40 years and experiencing headache between 3 - 6 months were found to have association with abnonnalities detected with adjusted OR 0.191 (0.07, 0.51) and 4.86 (1.37, 17.26) respectively. Intracranial abnormalities detected by FLAIR sequence were white matter lesions, meningioma, teratoma, meningo-encephalitis and intracranial haemorrhages. On the other hand, FLAIR missed to detect a small sub-ependymal nodule and arachnoid cyst in CSF spaces. CONCLUSION: Since FLAIR sequence is sensitive in detecting intracranial lesions, it can be used as a screening sequence in patients with headache but no neurological deficit. The MR examination time can be shortened and the number of patients for MR examination per day can be increased. 2007 Thesis http://eprints.usm.my/48436/ http://eprints.usm.my/48436/1/DR%20WAN%20DAIZYREENA%20BINTI%20WAN%20JAAFAR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Jaafar, Wan Daizyreena Wan The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
description	OBJECTIVES: The objectives of this study were to detennine prevalence and associated factors of intracranial lesions on :MRI examination and the accuracy of FLAIR in detecting intracranial lesions in patients with headache but no neurological deficit. METHOD: A retrospective and prospective cross-sectional study was perfonned over 51 months from 1 st June 2002 until 30th September 2006. One hundred and forty-three patients with headache but no neurological deficit aged 13 years old and above who had underwent routine :MRI examination of brain in Hospital University Sains Malaysia were included into this study. For each case, FLAIR sequence and complete brain series were reviewed separately at different times by two radiologists. RESULTS: Prevalence of intracranial lesions on complete MRI sequence was 18.9% (95% CI: 0.06, 0.32). The sensitivity for FLAIR was 92.6% and the specificity of 92.2%. Age more than 40 years and experiencing headache between 3 - 6 months were found to have association with abnonnalities detected with adjusted OR 0.191 (0.07, 0.51) and 4.86 (1.37, 17.26) respectively. Intracranial abnormalities detected by FLAIR sequence were white matter lesions, meningioma, teratoma, meningo-encephalitis and intracranial haemorrhages. On the other hand, FLAIR missed to detect a small sub-ependymal nodule and arachnoid cyst in CSF spaces. CONCLUSION: Since FLAIR sequence is sensitive in detecting intracranial lesions, it can be used as a screening sequence in patients with headache but no neurological deficit. The MR examination time can be shortened and the number of patients for MR examination per day can be increased.
format	Thesis
qualification_level	Master's degree
author	Jaafar, Wan Daizyreena Wan
author_facet	Jaafar, Wan Daizyreena Wan
author_sort	Jaafar, Wan Daizyreena Wan
title	The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
title_short	The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
title_full	The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
title_fullStr	The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
title_full_unstemmed	The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
title_sort	prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2007
url	http://eprints.usm.my/48436/1/DR%20WAN%20DAIZYREENA%20BINTI%20WAN%20JAAFAR.pdf
_version_	1747821932798017536

The prevalence and associated factors of intracranial lesions on mri and the accuracy of flair sequence in patients with headache but no neurological deficit.

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