Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018

Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018

Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems– 5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018 Background: Perforated peptic ulcer has a high morbidity and mortality. Existing scoring systems to...

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Main Author: Alias, Juliana
Format: Thesis
Language:English
Published: 2020
Subjects:
R Medicine
Online Access:http://eprints.usm.my/49386/1/Juliana%20Alias-24%20pages.pdf
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spelling my-usm-ep.493862021-07-04T14:49:20Z Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018 2020 Alias, Juliana R Medicine Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems– 5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018 Background: Perforated peptic ulcer has a high morbidity and mortality. Existing scoring systems to stratify patient at risk of mortality are American Society of Anasthesiologists (ASA), Boey and Peptic Ulcer Perforation (PULP) scores. The aim of this study was to determine 30-day mortality for perforated peptic ulcer patients operated in Hospital Sultanah Nurzahirah and secondary aim was to determine the accuracy of the three scoring systems. Methods: This is a retrospective review of patients surgically treated for perforated peptic ulcer in a tertiary hospital in Terengganu from January 2014 to December 2018. Clinical data and operative details were collected. Sensitivity, specificity, and area under the receiver operating curve (AUC) were compared between each scoring systems. Results: A total of 120 patients were included in this study of which 39 (32.5%) died within 30 days. Size of ulcer (p=0.039), site of ulcer (p=0.003), operation type (p=0.001), leakage (p=0.005) and abdominal collection (p=0.001) were significantly associated with mortality. Among the scoring systems, ASA has lowest predictive value for mortality (AUC 0.605) while Boey and PULP has similar moderate predictive value for mortality with AUC of 0.686 and 0.684 respectively. Conclusion: ASA, Boey and PULP has similar moderate accuracy to predict 30-day mortality in PPU, with ASA has the lowest predictive value. 2020 Thesis http://eprints.usm.my/49386/ http://eprints.usm.my/49386/1/Juliana%20Alias-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine
spellingShingle R Medicine
Alias, Juliana
Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
description Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems– 5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018 Background: Perforated peptic ulcer has a high morbidity and mortality. Existing scoring systems to stratify patient at risk of mortality are American Society of Anasthesiologists (ASA), Boey and Peptic Ulcer Perforation (PULP) scores. The aim of this study was to determine 30-day mortality for perforated peptic ulcer patients operated in Hospital Sultanah Nurzahirah and secondary aim was to determine the accuracy of the three scoring systems. Methods: This is a retrospective review of patients surgically treated for perforated peptic ulcer in a tertiary hospital in Terengganu from January 2014 to December 2018. Clinical data and operative details were collected. Sensitivity, specificity, and area under the receiver operating curve (AUC) were compared between each scoring systems. Results: A total of 120 patients were included in this study of which 39 (32.5%) died within 30 days. Size of ulcer (p=0.039), site of ulcer (p=0.003), operation type (p=0.001), leakage (p=0.005) and abdominal collection (p=0.001) were significantly associated with mortality. Among the scoring systems, ASA has lowest predictive value for mortality (AUC 0.605) while Boey and PULP has similar moderate predictive value for mortality with AUC of 0.686 and 0.684 respectively. Conclusion: ASA, Boey and PULP has similar moderate accuracy to predict 30-day mortality in PPU, with ASA has the lowest predictive value.
format Thesis
qualification_level Master's degree
author Alias, Juliana
author_facet Alias, Juliana
author_sort Alias, Juliana
title Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
title_short Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
title_full Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
title_fullStr Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
title_full_unstemmed Determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in Hospital Sultanah Nurzahirah from January 2014 to December 2018
title_sort determination of 30-day mortality in perforated peptic ulcer based on three existing scoring systems-5-year retrospective review in hospital sultanah nurzahirah from january 2014 to december 2018
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2020
url http://eprints.usm.my/49386/1/Juliana%20Alias-24%20pages.pdf
_version_ 1747821994703847424

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