A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia

Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information...

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Main Author:	Abidin, Muhd Abdul Ghani Zenol
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RD Surgery
Online Access:	http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf
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spelling	my-usm-ep.502972021-10-17T04:55:35Z A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia 2020 Abidin, Muhd Abdul Ghani Zenol RD Surgery Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information on the effect of bariatric surgery in this centre is lacking. Methods: This retrospective study involving review of medical records of all patients underwent sleeve gastrectomy or Roux-en-Y gastric bypass in Hospital Universiti Sains Malaysia between October 2016 until July 2019. We analyse weight, blood pressure and biochemical parameters at baseline and 6 months post-surgery using student paired t-test. McNemar test is used to determine change in oral hypoglycaemic agents and/or total insulin dose, total number of anti-hypertensives and total number of anti-lipids. Result: A total of 39 patients were analysed. Mean weight reduction was 29.14 (95% CI = 24.75, 33.53) kg, SBP mean reduction was 17.87 (95% CI = 11.17, 24.58) mmHg and DBP mean reduction was 7.18 (95% CI = 3.21, 11.15) mmHg. Mean HbA1c reduction was 3.13 (95% CI = 2.07, 4.19) %, triglycerides mean reduction of 0.29 (95% CI = 0.12, 0.47) mmol/L. At 6 months post-surgery, 16 participants (61%) had remission in hypertension, 41% had reduction in number of antihypertensive. Eight patients (40%) had remission of diabetes and 4 patients (20%) who were diabetics becoming pre-diabetes. Only 4 patients were on oral hypoglycaemic agents and/or 3 patients were able to off insulin. Total insulin dose were markedly reduced, with median dose of 148 (34) iu to 24 (34) post-operatively. Five patients (25%) had normalisation of lipid profile and were able to off anti-lipids. Conclusion: Bariatric surgery among our patients with obesity confers significant metabolic benefits which is comparable to other centres. 2020 Thesis http://eprints.usm.my/50297/ http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RD Surgery
spellingShingle	RD Surgery Abidin, Muhd Abdul Ghani Zenol A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
description	Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information on the effect of bariatric surgery in this centre is lacking. Methods: This retrospective study involving review of medical records of all patients underwent sleeve gastrectomy or Roux-en-Y gastric bypass in Hospital Universiti Sains Malaysia between October 2016 until July 2019. We analyse weight, blood pressure and biochemical parameters at baseline and 6 months post-surgery using student paired t-test. McNemar test is used to determine change in oral hypoglycaemic agents and/or total insulin dose, total number of anti-hypertensives and total number of anti-lipids. Result: A total of 39 patients were analysed. Mean weight reduction was 29.14 (95% CI = 24.75, 33.53) kg, SBP mean reduction was 17.87 (95% CI = 11.17, 24.58) mmHg and DBP mean reduction was 7.18 (95% CI = 3.21, 11.15) mmHg. Mean HbA1c reduction was 3.13 (95% CI = 2.07, 4.19) %, triglycerides mean reduction of 0.29 (95% CI = 0.12, 0.47) mmol/L. At 6 months post-surgery, 16 participants (61%) had remission in hypertension, 41% had reduction in number of antihypertensive. Eight patients (40%) had remission of diabetes and 4 patients (20%) who were diabetics becoming pre-diabetes. Only 4 patients were on oral hypoglycaemic agents and/or 3 patients were able to off insulin. Total insulin dose were markedly reduced, with median dose of 148 (34) iu to 24 (34) post-operatively. Five patients (25%) had normalisation of lipid profile and were able to off anti-lipids. Conclusion: Bariatric surgery among our patients with obesity confers significant metabolic benefits which is comparable to other centres.
format	Thesis
qualification_level	Master's degree
author	Abidin, Muhd Abdul Ghani Zenol
author_facet	Abidin, Muhd Abdul Ghani Zenol
author_sort	Abidin, Muhd Abdul Ghani Zenol
title	A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_short	A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_full	A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_fullStr	A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_full_unstemmed	A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_sort	study on the metabolic outcome of patients who underwent bariatric surgery in hospital universiti sains malaysia
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf
_version_	1747822031715434496

A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia

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