Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial

Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare t...

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Main Author: Helmi, Muhd Alwi Muhd
Format: Thesis
Language:English
Published: 2020
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Online Access:http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf
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spelling my-usm-ep.503062021-10-18T05:52:42Z Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial 2020 Helmi, Muhd Alwi Muhd R Medicine Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between Continuous Glucose Monitoring System (CGMS) and Self-Monitoring Blood Glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children. 2020 Thesis http://eprints.usm.my/50306/ http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine
spellingShingle R Medicine
Helmi, Muhd Alwi Muhd
Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
description Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between Continuous Glucose Monitoring System (CGMS) and Self-Monitoring Blood Glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children.
format Thesis
qualification_level Master's degree
author Helmi, Muhd Alwi Muhd
author_facet Helmi, Muhd Alwi Muhd
author_sort Helmi, Muhd Alwi Muhd
title Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_short Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_full Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_fullStr Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_full_unstemmed Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_sort continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (rosec) : a randomized controlled trial
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2020
url http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf
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