Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers

This study evaluates the radiation dosimetry effects of using virtual-bolus (VB) in TomoTherapy Treatment Planning System (TPS) for Planning-Target-Volume (PTV) that extends to skin or body-surface. PTV was contoured on phantom that extended to the phantom surface. Virtual bolus of various thickness...

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Main Author:	Ooi, Gim Chee
Format:	Thesis
Language:	English
Published:	2020
Subjects:	QC1 Physics (General)
Online Access:	http://eprints.usm.my/51679/1/OOI%20GIM%20CHEE%20-%20TESIS%20cut.pdf
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id	my-usm-ep.51679
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spelling	my-usm-ep.516792022-02-27T05:04:31Z Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers 2020-06 Ooi, Gim Chee QC1 Physics (General) This study evaluates the radiation dosimetry effects of using virtual-bolus (VB) in TomoTherapy Treatment Planning System (TPS) for Planning-Target-Volume (PTV) that extends to skin or body-surface. PTV was contoured on phantom that extended to the phantom surface. Virtual bolus of various thickness (0.2 cm / 0.4 cm / 0.6 cm) and densities (0.5 g/cm3 or 1.0 g/cm3) combinations were drawn to provide “virtual” build-up region for the TPS and then optimized with TomoTherapy TPS. EBT3 Gafchromic Film was calibrated and used to analyze the dose profiles across PTV and the phantom surface, and gamma analysis was peformed for the photon fluence with Distance-to-Agreement (DTA) 3 mm and Dose Difference 3% criteria. TomoTherapy Planned-Adaptive software was used to analyze the delivered Dose-Volume-Histograms (DVHs) reconstructed from the mega-voltage computed tomography (MVCT) acquisition. Without VB used, the control set optimization showed maximum dose close to 110% at the phantom edge or the surface due to lack of build-up region. VB of 0.2 cm was shown to be unable to provide adequate build-up area. The use of VBs of 0.4 cm and 0.6 cm for dose optimization were able to control the maximum dose in the TPS and also in the actual radiation delivery. However, VB of 0.6 cm exhibited large reduction in dose coverage (95%) in the actual radiation delivery. 2020-06 Thesis http://eprints.usm.my/51679/ http://eprints.usm.my/51679/1/OOI%20GIM%20CHEE%20-%20TESIS%20cut.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Fizik
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	QC1 Physics (General)
spellingShingle	QC1 Physics (General) Ooi, Gim Chee Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
description	This study evaluates the radiation dosimetry effects of using virtual-bolus (VB) in TomoTherapy Treatment Planning System (TPS) for Planning-Target-Volume (PTV) that extends to skin or body-surface. PTV was contoured on phantom that extended to the phantom surface. Virtual bolus of various thickness (0.2 cm / 0.4 cm / 0.6 cm) and densities (0.5 g/cm3 or 1.0 g/cm3) combinations were drawn to provide “virtual” build-up region for the TPS and then optimized with TomoTherapy TPS. EBT3 Gafchromic Film was calibrated and used to analyze the dose profiles across PTV and the phantom surface, and gamma analysis was peformed for the photon fluence with Distance-to-Agreement (DTA) 3 mm and Dose Difference 3% criteria. TomoTherapy Planned-Adaptive software was used to analyze the delivered Dose-Volume-Histograms (DVHs) reconstructed from the mega-voltage computed tomography (MVCT) acquisition. Without VB used, the control set optimization showed maximum dose close to 110% at the phantom edge or the surface due to lack of build-up region. VB of 0.2 cm was shown to be unable to provide adequate build-up area. The use of VBs of 0.4 cm and 0.6 cm for dose optimization were able to control the maximum dose in the TPS and also in the actual radiation delivery. However, VB of 0.6 cm exhibited large reduction in dose coverage (95%) in the actual radiation delivery.
format	Thesis
qualification_level	Master's degree
author	Ooi, Gim Chee
author_facet	Ooi, Gim Chee
author_sort	Ooi, Gim Chee
title	Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
title_short	Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
title_full	Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
title_fullStr	Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
title_full_unstemmed	Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers
title_sort	evaluation of virtual bolus for tomotherapy dose optimization in superficial cancers
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Fizik
publishDate	2020
url	http://eprints.usm.my/51679/1/OOI%20GIM%20CHEE%20-%20TESIS%20cut.pdf
_version_	1747822093660061696

Evaluation Of Virtual Bolus For Tomotherapy Dose Optimization In Superficial Cancers

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