The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery

Background Brachial plexus block is the preferred method of anaesthesia for Arteriovenous fistula (AVF) creation in End-Stage Renal Failure (ESRF) patients. Dexmedetomidine is an adjuvant used to improve the outcome of the block. The objective of this study was to investigate the efficacy of adding...

Full description

Saved in:

Bibliographic Details
Main Author:	Mutthusamy, Prakash Seelan
Format:	Thesis
Language:	English
Published:	2020
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/51865/1/Parakash%20Seelan%20Muthusamy-24%20pages.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.51865
record_format	uketd_dc
spelling	my-usm-ep.518652022-03-10T07:28:35Z The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery 2020 Mutthusamy, Prakash Seelan R Medicine Background Brachial plexus block is the preferred method of anaesthesia for Arteriovenous fistula (AVF) creation in End-Stage Renal Failure (ESRF) patients. Dexmedetomidine is an adjuvant used to improve the outcome of the block. The objective of this study was to investigate the efficacy of adding dexmedetomidine 100mcg to ropivacaine 0.25% in supraclavicular block. Methods 68 ESRF patients scheduled for AVF surgery were studied in a prospective, randomized, double-blind controlled clinical trial. They were divided into 2 groups; patients in group D receive a mixture of 30 mls of ropivacaine 0.25% and 1 ml (100 mcg) dexmedetomidine whilst patient in group C receive mixture of 30 mls of ropivacaine 0.5% and 1 ml of 0.9% normal saline. The primary endpoint was the onset and duration of sensory and motor block while secondary endpoint was to score patient and surgeon satisfaction. Results The onset time of sensory block in group D [15.29(3.24)] min was earlier than group C [18.09(3.26)] min and statistically significant (p < 0.001) while the onset time of motor block earlier in group C compare to group D but not statistically significant (p= 0.71). Both sensory and motor block durations were significantly longer in group D then group C with statistically significant (p< 0.001). In terms of satisfaction scoring group D has better scoring compare to group C among both surgeons and patients (p < 0.001). Conclusion: Low dose ropivacaine 0.25% with adjuvant of dexmedetomidine 100mcg is non inferior to the control group in providing anaesthesia for ESRF patients in AVF surgery. 2020 Thesis http://eprints.usm.my/51865/ http://eprints.usm.my/51865/1/Parakash%20Seelan%20Muthusamy-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Mutthusamy, Prakash Seelan The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
description	Background Brachial plexus block is the preferred method of anaesthesia for Arteriovenous fistula (AVF) creation in End-Stage Renal Failure (ESRF) patients. Dexmedetomidine is an adjuvant used to improve the outcome of the block. The objective of this study was to investigate the efficacy of adding dexmedetomidine 100mcg to ropivacaine 0.25% in supraclavicular block. Methods 68 ESRF patients scheduled for AVF surgery were studied in a prospective, randomized, double-blind controlled clinical trial. They were divided into 2 groups; patients in group D receive a mixture of 30 mls of ropivacaine 0.25% and 1 ml (100 mcg) dexmedetomidine whilst patient in group C receive mixture of 30 mls of ropivacaine 0.5% and 1 ml of 0.9% normal saline. The primary endpoint was the onset and duration of sensory and motor block while secondary endpoint was to score patient and surgeon satisfaction. Results The onset time of sensory block in group D [15.29(3.24)] min was earlier than group C [18.09(3.26)] min and statistically significant (p < 0.001) while the onset time of motor block earlier in group C compare to group D but not statistically significant (p= 0.71). Both sensory and motor block durations were significantly longer in group D then group C with statistically significant (p< 0.001). In terms of satisfaction scoring group D has better scoring compare to group C among both surgeons and patients (p < 0.001). Conclusion: Low dose ropivacaine 0.25% with adjuvant of dexmedetomidine 100mcg is non inferior to the control group in providing anaesthesia for ESRF patients in AVF surgery.
format	Thesis
qualification_level	Master's degree
author	Mutthusamy, Prakash Seelan
author_facet	Mutthusamy, Prakash Seelan
author_sort	Mutthusamy, Prakash Seelan
title	The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
title_short	The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
title_full	The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
title_fullStr	The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
title_full_unstemmed	The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
title_sort	efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/51865/1/Parakash%20Seelan%20Muthusamy-24%20pages.pdf
_version_	1747822107851489280

The efficacy of dexmedetomidine 100mcg as an adjuvant to 0.25% ropivacaive versus 0.5% plain ropivacaine for supraclavicular brachial plexus block in arteriovenuos fistula surgery

Similar Items