Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety

Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety

A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and...

Full description

Saved in:
Bibliographic Details
Main Author: Ng, Weng Zhun
Format: Thesis
Language:English
Published: 2021
Subjects:
QC1 Physics (General)
Online Access:http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.52192
record_format uketd_dc
spelling my-usm-ep.521922022-04-05T08:08:35Z Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety 2021-03 Ng, Weng Zhun QC1 Physics (General) A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group 2021-03 Thesis http://eprints.usm.my/52192/ http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf application/pdf en public masters Perpustakaan Hamzah Sendut Pusat Pengajian Sains Fizik
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic QC1 Physics (General)
spellingShingle QC1 Physics (General)
Ng, Weng Zhun
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
description A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group
format Thesis
qualification_level Master's degree
author Ng, Weng Zhun
author_facet Ng, Weng Zhun
author_sort Ng, Weng Zhun
title Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
title_short Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
title_full Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
title_fullStr Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
title_full_unstemmed Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
title_sort synthesis, x-ray structure characterization and antioxidant activities of some chalcone derivatives containing 2-chlorothiophene moiety
granting_institution Perpustakaan Hamzah Sendut
granting_department Pusat Pengajian Sains Fizik
publishDate 2021
url http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf
_version_ 1747822143701254144

Similar Items