Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety
A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and...
Saved in:
| 主要作者: | |
|---|---|
| 格式: | Thesis |
| 语言: | English |
| 出版: |
2021
|
| 主题: | |
| 在线阅读: | http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf |
| 标签: |
添加标签
没有标签, 成为第一个标记此记录!
|
| id |
my-usm-ep.52192 |
|---|---|
| record_format |
uketd_dc |
| spelling |
my-usm-ep.521922022-04-05T08:08:35Z Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety 2021-03 Ng, Weng Zhun QC1 Physics (General) A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group 2021-03 Thesis http://eprints.usm.my/52192/ http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf application/pdf en public masters Perpustakaan Hamzah Sendut Pusat Pengajian Sains Fizik |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
QC1 Physics (General) |
| spellingShingle |
QC1 Physics (General) Ng, Weng Zhun Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| description |
A total of twelve heterocyclic chalcone compounds (1a-1l) containing 2-chlorothiophene moieties were synthesized using Claisen Schmidt Condensation process and were crystallized by slow evaporation methods. The postulate structure of these heterocyclic chalcone compounds were elucidated by FT-IR and NMR spectral analyses, followed by single crystal X-ray diffraction technique. Besides, the antioxidant potential of all compounds was evaluated using four different types of antioxidant assay which include 2, 2-diphenyl-1-picrylhydrazyl (DPPH), ferrous ion chelating (FIC), nitric oxide (NO) and Hydrogen Peroxide (H2O2) radical scavenging assay. Nine compounds are crystallized in monoclinic space group with four compounds in P21/c, three compounds in P21/n and two compounds in Cc and Pc. Another, two compounds are crystallized in triclinic space group |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Ng, Weng Zhun |
| author_facet |
Ng, Weng Zhun |
| author_sort |
Ng, Weng Zhun |
| title |
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_short |
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_full |
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_fullStr |
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_full_unstemmed |
Synthesis, X-Ray Structure Characterization And Antioxidant Activities Of Some Chalcone Derivatives Containing 2-Chlorothiophene Moiety |
| title_sort |
synthesis, x-ray structure characterization and antioxidant activities of some chalcone derivatives containing 2-chlorothiophene moiety |
| granting_institution |
Perpustakaan Hamzah Sendut |
| granting_department |
Pusat Pengajian Sains Fizik |
| publishDate |
2021 |
| url |
http://eprints.usm.my/52192/1/NG%20WENG%20ZHUN%20-%20TESIS.pdf |
| _version_ |
1747822143701254144 |