Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago

Amphibians are the most diverse terrestrial vertebrates and are essential for conserving the environment since they act as biological indicators. Furthermore, frogs were one of the primary sources of bioactive compounds for biomedical and pharmaceutical applications. A total of 24 species of amphibi...

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Main Author: Ridzuan, Fakhitah
Format: Thesis
Language:English
Published: 2021
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Online Access:http://eprints.usm.my/52690/1/DASI%20ONG%20BINTI%20YAQUT%20ONG%20-%20TESIS24.pdf
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spelling my-usm-ep.526902022-05-31T16:43:24Z Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago 2021-10 Ridzuan, Fakhitah RS1-441 Pharmacy and materia medica Amphibians are the most diverse terrestrial vertebrates and are essential for conserving the environment since they act as biological indicators. Furthermore, frogs were one of the primary sources of bioactive compounds for biomedical and pharmaceutical applications. A total of 24 species of amphibians from six families were documented within Langkawi Archipelago. The 95% confidence rarefaction species accumulation curve of amphibian species within the Langkawi Archipelago reaches a plateau, shows that all species are found in this study with the effort invested. Compared to previous studies, the absent species in this study were Ingerophrynus parvus, Limnonectes malesianus, Occidozyga lima, Raorchestes parvulus, Rhacophorus bipunctatus, and Amolops larutensis. Moreover, an additional species was recorded- Pulchrana laterimaculata. Non-Multi-Dimensional Scaling analysis of amphibian habitat assemblage categorised these 24 species into eight groups according to their habitat preference and forest assemblage. For protein anti-microbial composition analysis, a medium-sized adult individual of each species- Odorrana hosii, Pulchrana glandulosa, Chalcorana labialis, and Hylarana erythraea, were collected from their natural habitat. Using liquid chromatography-mass spectrometry (LC-MS), these frogs’ skin secretions were collected, extracted, and analysed for their protein compounds using liquid chromatography-mass spectrometry (LC-MS). 2021-10 Thesis http://eprints.usm.my/52690/ http://eprints.usm.my/52690/1/DASI%20ONG%20BINTI%20YAQUT%20ONG%20-%20TESIS24.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Ridzuan, Fakhitah
Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
description Amphibians are the most diverse terrestrial vertebrates and are essential for conserving the environment since they act as biological indicators. Furthermore, frogs were one of the primary sources of bioactive compounds for biomedical and pharmaceutical applications. A total of 24 species of amphibians from six families were documented within Langkawi Archipelago. The 95% confidence rarefaction species accumulation curve of amphibian species within the Langkawi Archipelago reaches a plateau, shows that all species are found in this study with the effort invested. Compared to previous studies, the absent species in this study were Ingerophrynus parvus, Limnonectes malesianus, Occidozyga lima, Raorchestes parvulus, Rhacophorus bipunctatus, and Amolops larutensis. Moreover, an additional species was recorded- Pulchrana laterimaculata. Non-Multi-Dimensional Scaling analysis of amphibian habitat assemblage categorised these 24 species into eight groups according to their habitat preference and forest assemblage. For protein anti-microbial composition analysis, a medium-sized adult individual of each species- Odorrana hosii, Pulchrana glandulosa, Chalcorana labialis, and Hylarana erythraea, were collected from their natural habitat. Using liquid chromatography-mass spectrometry (LC-MS), these frogs’ skin secretions were collected, extracted, and analysed for their protein compounds using liquid chromatography-mass spectrometry (LC-MS).
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Ridzuan, Fakhitah
author_facet Ridzuan, Fakhitah
author_sort Ridzuan, Fakhitah
title Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
title_short Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
title_full Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
title_fullStr Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
title_full_unstemmed Protein Anti-microbial Potential Of The Skin Secretion Of Human Commensal And Forest Edge Frog (Anuran) Species From Langkawi Archipelago
title_sort protein anti-microbial potential of the skin secretion of human commensal and forest edge frog (anuran) species from langkawi archipelago
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2021
url http://eprints.usm.my/52690/1/DASI%20ONG%20BINTI%20YAQUT%20ONG%20-%20TESIS24.pdf
_version_ 1747822204209332224