In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration

Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. R...

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Main Author:	Tan, Florence Hui Ping
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf
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spelling	my-usm-ep.533942022-07-15T08:33:47Z In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration 2020-12 Tan, Florence Hui Ping RS1-441 Pharmacy and materia medica Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. Regardless of the immense research on AD, the full pathogenesis of this disease remains unknown. The main aim of this study was to identify compounds that are able to alleviate Aβ42’s negative effects. 2020-12 Thesis http://eprints.usm.my/53394/ http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi (School of Pharmacy)
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Tan, Florence Hui Ping In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
description	Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. Regardless of the immense research on AD, the full pathogenesis of this disease remains unknown. The main aim of this study was to identify compounds that are able to alleviate Aβ42’s negative effects.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Tan, Florence Hui Ping
author_facet	Tan, Florence Hui Ping
author_sort	Tan, Florence Hui Ping
title	In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
title_short	In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
title_full	In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
title_fullStr	In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
title_full_unstemmed	In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
title_sort	in vitro and in vivo study on the identification of compounds that alleviate aβ42 associated neurodegeneration
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi (School of Pharmacy)
publishDate	2020
url	http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf
_version_	1747822239059804160

In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration

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