Valuation Of Eq-5d-5l Study For The Malaysian Population

With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes i...

Full description

Saved in:

Bibliographic Details
Main Author:	Thakumar, Annushiah Vasan
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/54900/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.54900
record_format	uketd_dc
spelling	my-usm-ep.549002022-09-23T02:56:08Z Valuation Of Eq-5d-5l Study For The Malaysian Population 2020-07 Thakumar, Annushiah Vasan RS1-441 Pharmacy and materia medica With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques. Another value set was estimated, but applying an earlier version of the instrument, EQ-5D-3L. 2020-07 Thesis http://eprints.usm.my/54900/ http://eprints.usm.my/54900/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Thakumar, Annushiah Vasan Valuation Of Eq-5d-5l Study For The Malaysian Population
description	With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques. Another value set was estimated, but applying an earlier version of the instrument, EQ-5D-3L.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Thakumar, Annushiah Vasan
author_facet	Thakumar, Annushiah Vasan
author_sort	Thakumar, Annushiah Vasan
title	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_short	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_fullStr	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full_unstemmed	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_sort	valuation of eq-5d-5l study for the malaysian population
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2020
url	http://eprints.usm.my/54900/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
_version_	1747822298542374912

Valuation Of Eq-5d-5l Study For The Malaysian Population

Similar Items