Valuation Of Eq-5d-5l Study For The Malaysian Population

With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes i...

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Main Author:	Thakumar, Annushiah Vasan
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
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id	my-usm-ep.54974
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spelling	my-usm-ep.549742022-09-28T07:24:09Z Valuation Of Eq-5d-5l Study For The Malaysian Population 2020-07 Thakumar, Annushiah Vasan RS1-441 Pharmacy and materia medica With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques. 2020-07 Thesis http://eprints.usm.my/54974/ http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Thakumar, Annushiah Vasan Valuation Of Eq-5d-5l Study For The Malaysian Population
description	With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Thakumar, Annushiah Vasan
author_facet	Thakumar, Annushiah Vasan
author_sort	Thakumar, Annushiah Vasan
title	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_short	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_fullStr	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full_unstemmed	Valuation Of Eq-5d-5l Study For The Malaysian Population
title_sort	valuation of eq-5d-5l study for the malaysian population
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2020
url	http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
_version_	1747822301740531712

Valuation Of Eq-5d-5l Study For The Malaysian Population

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