Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds

Polyhydroxyalkanoates (PHAs) are polyesters produced by microorganisms under unbalanced growth conditions. They are well documented as a biodegradable and biocompatible polymer, making them attractive as biomaterials for applications in tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoat...

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Main Author:	Ang, Shaik Ling
Format:	Thesis
Language:	English
Published:	2019
Subjects:	QH1-278.5 Natural history (General)
Online Access:	http://eprints.usm.my/55696/1/24%20Pages%20from%20Ang%20Shaik%20Ling.pdf
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id	my-usm-ep.55696
record_format	uketd_dc
spelling	my-usm-ep.556962022-11-17T07:03:33Z Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds 2019-12 Ang, Shaik Ling QH1-278.5 Natural history (General) Polyhydroxyalkanoates (PHAs) are polyesters produced by microorganisms under unbalanced growth conditions. They are well documented as a biodegradable and biocompatible polymer, making them attractive as biomaterials for applications in tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) P(3HB-co-3HHx) is one of the members of the PHA family that has shown superior mechanical properties and processability compared to poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [(P(3HB-co-3HV)]. However, the biocompatibility of P(3HB-co-3HHx) is still inadequate because of its hydrophobic properties that has hampered its direct use as scaffold material. In this study, silk fibroin (SF) derived from Bombyx mori cocoons, which is a widely used and studied protein polymer for biomaterial applications have been used to improve the cell affinity and biocompatibility of P(3HB-co-3HHx). 2019-12 Thesis http://eprints.usm.my/55696/ http://eprints.usm.my/55696/1/24%20Pages%20from%20Ang%20Shaik%20Ling.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Kajihayat
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	QH1-278.5 Natural history (General)
spellingShingle	QH1-278.5 Natural history (General) Ang, Shaik Ling Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
description	Polyhydroxyalkanoates (PHAs) are polyesters produced by microorganisms under unbalanced growth conditions. They are well documented as a biodegradable and biocompatible polymer, making them attractive as biomaterials for applications in tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) P(3HB-co-3HHx) is one of the members of the PHA family that has shown superior mechanical properties and processability compared to poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [(P(3HB-co-3HV)]. However, the biocompatibility of P(3HB-co-3HHx) is still inadequate because of its hydrophobic properties that has hampered its direct use as scaffold material. In this study, silk fibroin (SF) derived from Bombyx mori cocoons, which is a widely used and studied protein polymer for biomaterial applications have been used to improve the cell affinity and biocompatibility of P(3HB-co-3HHx).
format	Thesis
qualification_level	Master's degree
author	Ang, Shaik Ling
author_facet	Ang, Shaik Ling
author_sort	Ang, Shaik Ling
title	Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
title_short	Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
title_full	Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
title_fullStr	Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
title_full_unstemmed	Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds
title_sort	biocompatibility of electrospun bombyx mori silk fibroin with poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) as a biomaterial for tissue-engineered scaffolds
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kajihayat
publishDate	2019
url	http://eprints.usm.my/55696/1/24%20Pages%20from%20Ang%20Shaik%20Ling.pdf
_version_	1776101106773917696

Biocompatibility Of Electrospun Bombyx Mori Silk Fibroin With Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate) As A Biomaterial For Tissue-Engineered Scaffolds

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