Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study

Introduction: Exposure to alpha and gamma binaural beats (BB) have provided inconsistent findings in its modulating role of working memory (WM). White noise (WN) has acted as a control condition. Objective: The study aims to explore the effect of load on the effectiveness of WN embedded BB on WM...

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Main Author: Aloysius, Nursabrina Mohd Firdaus
Format: Thesis
Language:English
Published: 2021
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Online Access:http://eprints.usm.my/55733/1/Nursabrina%20Mohd%20Firdaus-24%20pages.pdf
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spelling my-usm-ep.557332022-11-23T07:58:44Z Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study 2021-08 Aloysius, Nursabrina Mohd Firdaus R Medicine Introduction: Exposure to alpha and gamma binaural beats (BB) have provided inconsistent findings in its modulating role of working memory (WM). White noise (WN) has acted as a control condition. Objective: The study aims to explore the effect of load on the effectiveness of WN embedded BB on WM performance using functional magnetic resonance imaging. Method: The research utilised experimental, block-design n-back task paradigm. Results: Six young adults (3 males and 3 females) within the Kota Bharu vicinity were recruited with mean age of 23.5 ± 0.84. The twoway repeated measures ANOVA (p<0.05) on response accuracy shows there is no significant main effect for conditions and load. The interaction effect of conditions and load on response accuracy (2=.171) demonstrates slight improvement in response accuracy The two-way repeated measures ANOVA (p<0.05) of reaction time (RT) shows a significant difference in the main effect of load, in particular during 1-back condition post BB. There is no interaction effect of conditions and load on RT. For GWN and AWN exposure, one sample t-test (p<0.05,uncorrected) suggests that the activation of posterior cingulate gyrus are associated with attentional modulation and supplementary motor area is closely related to WM mechanism respectively. Two-way repeated measures ANOVA (p<0.05,uncorrected) of the WM task further supports the aforementioned modulation in post-BB activations with the activation of thalamic regions in GWN and frontoparietal regions in AWN. Conclusion: The preliminary findings suggest that WN embedded BB should be considered further as a non-invasive WM improvement method amongst clinical and non-clinical population. 2021-08 Thesis http://eprints.usm.my/55733/ http://eprints.usm.my/55733/1/Nursabrina%20Mohd%20Firdaus-24%20pages.pdf application/pdf en public masters Universiti Sains Perubatan Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine
spellingShingle R Medicine
Aloysius, Nursabrina Mohd Firdaus
Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
description Introduction: Exposure to alpha and gamma binaural beats (BB) have provided inconsistent findings in its modulating role of working memory (WM). White noise (WN) has acted as a control condition. Objective: The study aims to explore the effect of load on the effectiveness of WN embedded BB on WM performance using functional magnetic resonance imaging. Method: The research utilised experimental, block-design n-back task paradigm. Results: Six young adults (3 males and 3 females) within the Kota Bharu vicinity were recruited with mean age of 23.5 ± 0.84. The twoway repeated measures ANOVA (p<0.05) on response accuracy shows there is no significant main effect for conditions and load. The interaction effect of conditions and load on response accuracy (2=.171) demonstrates slight improvement in response accuracy The two-way repeated measures ANOVA (p<0.05) of reaction time (RT) shows a significant difference in the main effect of load, in particular during 1-back condition post BB. There is no interaction effect of conditions and load on RT. For GWN and AWN exposure, one sample t-test (p<0.05,uncorrected) suggests that the activation of posterior cingulate gyrus are associated with attentional modulation and supplementary motor area is closely related to WM mechanism respectively. Two-way repeated measures ANOVA (p<0.05,uncorrected) of the WM task further supports the aforementioned modulation in post-BB activations with the activation of thalamic regions in GWN and frontoparietal regions in AWN. Conclusion: The preliminary findings suggest that WN embedded BB should be considered further as a non-invasive WM improvement method amongst clinical and non-clinical population.
format Thesis
qualification_level Master's degree
author Aloysius, Nursabrina Mohd Firdaus
author_facet Aloysius, Nursabrina Mohd Firdaus
author_sort Aloysius, Nursabrina Mohd Firdaus
title Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
title_short Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
title_full Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
title_fullStr Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
title_full_unstemmed Alpha and low gamma embedded with white noise binaural beats modulating working memory among Malaysian young adults: an exploratory fMRI study
title_sort alpha and low gamma embedded with white noise binaural beats modulating working memory among malaysian young adults: an exploratory fmri study
granting_institution Universiti Sains Perubatan
granting_department Pusat Pengajian Sains Perubatan
publishDate 2021
url http://eprints.usm.my/55733/1/Nursabrina%20Mohd%20Firdaus-24%20pages.pdf
_version_ 1776101110616948736